Evidence map›Paper›PMID 33241850›Full record

ReviewBiotechnology and bioengineering2021

Halophilic archaea and their potential to generate renewable fuels and chemicals.

Lakshmi Kasirajan, Julie A Maupin-Furlow

Open access · greenAbstract readReview
In one paragraph

Review in Biotechnology and bioengineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 36 citations in OpenAlex.

  1. Recent Advances in Understanding Bio-Compounds from Haloarchaea.Journal of microbiology and biotechnology · 2026
    Review
  2. Microbial conversion of biodiesel waste for carotenoid production.Frontiers in bioengineering and biotechnology · 2026
    Article
  3. Biotechnological Applications of Archaea.Progress in molecular and subcellular biology · 2026
    Review
  4. Phylogenomic and comparative analyses on protein sequences fromInternational journal of systematic and evolutionary microbiology · 2025
    Article
  5. Halocins and CMarine drugs · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Continuous bioreactor production of polyhydroxyalkanoates inFrontiers in bioengineering and biotechnology · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Industrial Biotechnology Based on Enzymes From Extreme Environments.Frontiers in bioengineering and biotechnology · 2022
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Lakshmi KasirajanDepartment of Microbiology and Cell Science, University of Florida, Gainesville, Florida, USA.ORCID 0000-0001-6620-9841
Julie A Maupin-FurlowDepartment of Microbiology and Cell Science, University of Florida, Gainesville, Florida, USA.ORCID 0000-0001-6105-0923
University of Florida · US

Funding

Ubiquitin-like Small Archaeal Protein Modification (SAMPylation)R01GM057498 · NIGMS · UNIVERSITY OF FLORIDA · PI MAUPIN-FURLOW, JULIE A · 2000 to 2024
$4.9M
NIGMS NIH HHS R01 GM057498
6 · The paper itself

Abstract

Lignocellulosic biofuels and chemicals have great potential to reduce our dependence on fossil fuels and mitigate air pollution by cutting down on greenhouse gas emissions. Chemical, thermal, and enzymatic processes are used to release the sugars from the lignocellulosic biomass for conversion to biofuels. These processes often operate at extreme pH conditions, high salt concentrations, and/or high temperature. These harsh treatments add to the cost of the biofuels, as most known biocatalysts do not operate under these conditions. To increase the economic feasibility of biofuel production, microorganisms that thrive in extreme conditions are considered as ideal resources to generate biofuels and value-added products. Halophilic archaea (haloarchaea) are isolated from hypersaline ecosystems with high salt concentrations approaching saturation (1.5-5 M salt concentration) including environments with extremes in pH and/or temperature. The unique traits of haloarchaea and their enzymes that enable them to sustain catalytic activity in these environments make them attractive resources for use in bioconversion processes that must occur across a wide range of industrial conditions. Biocatalysts (enzymes) derived from haloarchaea occupy a unique niche in organic solvent, salt-based, and detergent industries. This review focuses on the use of haloarchaea and their enzymes to develop and improve biofuel production. The review also highlights how haloarchaea produce value-added products, such as antibiotics, carotenoids, and bioplastic precursors, and can do so using feedstocks considered "too salty" for most microbial processes including wastes from the olive-mill, shell fish, and biodiesel industries.

Indexed as

BiofuelsHalobacterialesBiological ProductsHydrogen-Ion ConcentrationSalinitySodium ChlorideBiofuelsBiological ProductsSodium Chloridebiocompoundsbiodieselextremophileshydrolytic enzymeslignocellulosesaccharification

Identifiers

PMID33241850
PMCPMC7897274
OpenAlexW3109927416

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.