Evidence map›Paper›PMID 33241754›Full record

ArticleJournal of the American Heart Association2020

Baseline NT-proBNP Accurately Predicts Symptom Response to Transcatheter Aortic Valve Implantation.

Christopher J Allen, Jubin Joseph, Tiffany Patterson, Matthew Hammond-Haley, Hannah Z R McConkey, Bernard D Prendergast, Michael Marber, Simon R Redwood

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Christopher J AllenCardiovascular Division St. Thomas HospitalKing's College London London United Kingdom.
Jubin JosephCardiovascular Division St. Thomas HospitalKing's College London London United Kingdom.
Tiffany PattersonCardiovascular Division St. Thomas HospitalKing's College London London United Kingdom.
Matthew Hammond-HaleyDepartment of Cardiology Guys' and St Thomas NHS Foundation Trust London United Kingdom.
Hannah Z R McConkeyCardiovascular Division St. Thomas HospitalKing's College London London United Kingdom.
Bernard D PrendergastDepartment of Cardiology Guys' and St Thomas NHS Foundation Trust London United Kingdom.
Michael MarberCardiovascular Division St. Thomas HospitalKing's College London London United Kingdom.
Simon R RedwoodCardiovascular Division St. Thomas HospitalKing's College London London United Kingdom.
St Thomas' Hospital · GBGuy's and St Thomas' NHS Foundation Trust · GB

Funding

British Heart Foundation FS/15/52/31587British Heart Foundation FS/16/51/32365British Heart Foundation FS/18/48/33745Department of Health
6 · The paper itself

Abstract

Background Up to 30% of patients undergoing transcatheter aortic valve implantation (TAVI) experience minimal symptomatic benefit or die within 1 year, indicating an urgent need for enhanced patient selection. Previous analyses of baseline NT-proBNP (N-terminal pro-brain natriuretic peptide) and TAVI outcomes have assumed a linear relationship, yielding conflicting results. We reexamined the relationship between baseline NT-proBNP and symptomatic improvement after TAVI. Methods and Results Symptom status, clinical and echocardiographic data, and baseline NT-proBNP were reviewed from 144 consecutive patients undergoing TAVI for severe symptomatic aortic stenosis. The primary end point was change in New York Heart Association functional class at 1 year. There was a nonlinear, inverted-U relationship between log-baseline NT-proBNP and post-TAVI change in NYHA class (

Indexed as

Transcatheter Aortic Valve ReplacementAgedAged, 80 and overAortic Valve StenosisEchocardiographyFemaleHumansMaleNatriuretic Peptide, BrainPeptide FragmentsPredictive Value of TestsRetrospective StudiesROC CurveSymptom AssessmentTreatment OutcomeNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)aortic stenosisNT‐proBNPtranscutaneous aortic valve implantationtransfemoral aortic valve implantation

Identifiers

PMID33241754
PMCPMC7763793
OpenAlexW3109563123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.