Evidence map›Paper›PMID 33241750›Full record

ArticleJournal of the American Heart Association2020

Management of Atrial Fibrillation in Older Patients by Morbidity Burden: Insights From Get With The Guidelines-Atrial Fibrillation.

Frederik Dalgaard, Haolin Xu, Roland A Matsouaka, Andrea M Russo, Anne B Curtis, Peter Vibe Rasmussen, Martin H Ruwald, Gregg C Fonarow, Angela Lowenstern, Morten L Hansen and 8 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Association between comorbidity burden and outcomes of catheter ablation vs. medical therapy for atrial fibrillation: insights from the CABANA trial.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Observational
  11. Article
  12. Atrial fibrillation and stroke prevention: 25 years of research at EP Europace journal.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Review
  13. Article
  14. Article
  15. Review
  16. Observational
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Frederik DalgaardDepartment of Cardiology Herlev and Gentofte Hospital Hellerup Denmark.
Haolin XuDuke Clinical Research Institute Duke University Durham NC.
Roland A MatsouakaDuke Clinical Research Institute Duke University Durham NC.
Andrea M RussoCooper Medical School of Rowan University Camden NJ.
Anne B CurtisDepartment of Medicine University at Buffalo NY.
Peter Vibe RasmussenDepartment of Cardiology Herlev and Gentofte Hospital Hellerup Denmark.
Martin H RuwaldDepartment of Cardiology Herlev and Gentofte Hospital Hellerup Denmark.
Gregg C FonarowDivision of Cardiology Department of Medicine Ahmanson-UCLA Cardiomyopathy CenterRonald Reagan-UCLA Medical Center Los Angeles CA.
Angela LowensternDuke Clinical Research Institute Duke University Durham NC.
Morten L HansenDepartment of Cardiology Herlev and Gentofte Hospital Hellerup Denmark.
Jannik L PallisgaardDepartment of Cardiology Herlev and Gentofte Hospital Hellerup Denmark.
Karen P AlexanderDuke Clinical Research Institute Duke University Durham NC.
John H AlexanderDuke Clinical Research Institute Duke University Durham NC.
Renato D LopesDuke Clinical Research Institute Duke University Durham NC.
Christopher B GrangerDuke Clinical Research Institute Duke University Durham NC.
William R LewisDivision of Cardiology MetroHealth CampusCase Western Reserve University Cleveland OH.
Jonathan P PicciniDuke Clinical Research Institute Duke University Durham NC.
Sana M Al-KhatibDuke Clinical Research Institute Duke University Durham NC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Knowledge is scarce regarding how multimorbidity is associated with therapeutic decisions regarding oral anticoagulants (OACs) in patients with atrial fibrillation. Methods and Results We conducted a cross-sectional study of hospitalized patients with atrial fibrillation using the Get With The Guidelines-Atrial Fibrillation registry from 2013 to 2019. We identified patients ≥65 years and eligible for OAC therapy. Using 16 available comorbidity categories, patients were stratified by morbidity burden. A multivariable logistic regression model was used to determine the odds of receiving OAC prescription at discharge by morbidity burden. We included 34 174 patients with a median (interquartile range) age of 76 (71-83) years, 56.6% women, and 41.9% were not anticoagulated at admission. Of these patients, 38.6% had 0 to 2 comorbidities, 50.7% had 3 to 5 comorbidities, and 10.7% had ≥6 comorbidities. The overall discharge OAC prescription was high (85.6%). The prevalence of patients with multimorbidity increased from 59.7% in 2014 to 64.3% in 2019 (

Indexed as

Administration, OralAgedAged, 80 and overAge FactorsAnticoagulantsAtrial FibrillationCross-Sectional StudiesFemaleHospitalizationHumansLogistic ModelsMaleMultimorbidityOdds RatioPractice Guidelines as TopicPractice Patterns, Physicians'Anticoagulantsanticoagulationatrial fibrillationcomorbiditiesmultimorbidityoral anticoagulantsprescriptionquality of care

Identifiers

PMID33241750
PMCPMC7763767

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.