Evidence map›Paper›PMID 33241447›Full record

ArticleMolecular biology reports2020

Enteromorpha compressa extract induces anticancer activity through apoptosis and autophagy in oral cancer.

Biswajita Pradhan, Srimanta Patra, Chhandashree Behera, Rabindra Nayak, Shankargouda Patil, Sujit K Bhutia, Mrutyunjay Jena

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 41 citations in OpenAlex.

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  5. Pro-Apoptotic Activity and Cell Cycle Arrest ofMolecules (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Biswajita PradhanAlgal Biotechnology and Molecular Systematic Laboratory, Post Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur, Odisha, 760007, India.
Srimanta PatraCancer and Cell Death Laboratory, Department of Life Science, National Institute of Technology Rourkela, Rourkela, Odisha, 769008, India.
Chhandashree BeheraAlgal Biotechnology and Molecular Systematic Laboratory, Post Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur, Odisha, 760007, India.
Rabindra NayakAlgal Biotechnology and Molecular Systematic Laboratory, Post Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur, Odisha, 760007, India.
Shankargouda PatilDepartment of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia.
Sujit K BhutiaCancer and Cell Death Laboratory, Department of Life Science, National Institute of Technology Rourkela, Rourkela, Odisha, 769008, India.
Mrutyunjay JenaAlgal Biotechnology and Molecular Systematic Laboratory, Post Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur, Odisha, 760007, India. mrutyunjay.jena@gmail.com.ORCID http://orcid.org/0000-0003-2157-4292
Berhampur University · INNational Institute of Technology Rourkela · INJazan University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marine algae are an auspicious source of innovative bioactive compounds containing possible therapeutic agents against mammalian cancers. However, the mechanism by which bioactive algal compounds exhibit anticancer activity against oral squamous cell carcinoma (OSCC) is scant. The main objective of the current study was to explore the properties of the Enteromorpha compressa solvent extracts that induced autophagy and apoptosis with reference to their potent phytochemical and antioxidant properties. The presence of bioactive compounds were confirmed by UV and FT-IR spectroscopy. The free radical scavenging activity were analyzed by evaluating H

Indexed as

Antineoplastic Agents, PhytogenicAntioxidantsApoptosisAscorbate PeroxidasesAutophagyBiphenyl CompoundsCaspase 3Caspase 7CatalaseCell Line, TumorEpithelial CellsGene Expression Regulation, NeoplasticGlutathione PeroxidaseGlutathione ReductaseHumansHydrogen Peroxide1,1-diphenyl-2-picrylhydrazylAntineoplastic Agents, PhytogenicAntioxidantsAscorbate PeroxidasesBiphenyl CompoundsCASP3 protein, humanCASP7 protein, humanCaspase 3Caspase 7CatalaseGlutathione PeroxidaseGlutathione ReductaseHydrogen PeroxideMAP1LC3A protein, humanMicrotubule-Associated ProteinsPicratesPlant ExtractsSuperoxide DismutaseAntioxidantApoptosisAutophagyEnteromorpha compressaOral squamous cell carcinoma (OSCC)

Identifiers

PMID33241447
OpenAlexW3109669897

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.