Evidence map›Paper›PMID 33241435›Full record

ArticleMikrochimica acta2020

Fluorescent and electrochemical dual-mode detection of Chikungunya virus E1 protein using fluorophore-embedded and redox probe-encapsulated liposomes.

Fahmida Nasrin, Ankan Dutta Chowdhury, Akhilesh Babu Ganganboina, Ojodomo J Achadu, Farzana Hossain, Masahito Yamazaki, Enoch Y Park

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Fahmida NasrinLaboratory of Biotechnology, Graduate School of Science and Technology, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka, 422-8529, Japan.
Ankan Dutta ChowdhuryLaboratory of Biotechnology, Research Institute of Green Science and Technology, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka, 422-8529, Japan.
Akhilesh Babu GanganboinaLaboratory of Biotechnology, Research Institute of Green Science and Technology, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka, 422-8529, Japan.
Ojodomo J AchaduLaboratory of Biotechnology, Research Institute of Green Science and Technology, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka, 422-8529, Japan.
Farzana HossainLaboratory of Biotechnology, Graduate School of Science and Technology, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka, 422-8529, Japan.
Masahito YamazakiResearch Institute of Electronics, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka, 422-8529, Japan.
Enoch Y ParkLaboratory of Biotechnology, Graduate School of Science and Technology, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka, 422-8529, Japan. park.enoch@shizuoka.ac.jp.ORCID 0000-0002-7840-1424
Shizuoka University · JP

Funding

Japan Society for the Promotion of Science 19F19064Japan Society for the Promotion of Science 19F19348
6 · The paper itself

Abstract

The critical goal of sensitive virus detection should apply in the early stage of infection, which may increase the probable survival rate. To achieve the low detection limit for the early stage where a small number of viruses are present in the sample, proper amplified signals from a sensor can make readable and reliable detection. In this work, a new model of fluorescent and electrochemical dual-mode detection system has been developed to detect virus, taking recombinant Chikungunya virus E1 protein (CHIK-VP) as an example. The hydrophobic quantum dots (QDs) embedded in the lipid bilayer of liposome and methylene blue (MB) encapsulated in the inner core of liposomes played a role of dual-signaling modulator. After CHIK-VP addition, the nanocomposites and APTES-coated Fe

Indexed as

Antibodies, ViralChikungunya virusElectrochemical TechniquesFerrosoferric OxideFluorescent DyesFluorometryLimit of DetectionLiposomesMagnetite NanoparticlesMethylene BlueOxidation-ReductionQuantum DotsRecombinant ProteinsViral Envelope ProteinsAntibodies, ViralE1 envelope protein, Chikungunya virusFerrosoferric OxideFluorescent DyesLiposomesMagnetite NanoparticlesMethylene BlueRecombinant ProteinsViral Envelope ProteinsBiosensorChikungunya virus proteinElectrochemical detectionFluorescence detectionLiposomesQuantum dots

Identifiers

PMID33241435
PMCPMC7688297
OpenAlexW3108849047

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.