Evidence map›Paper›PMID 33241216›Full record

ArticleNeuro-oncology advances

Epidemiology of vestibular schwannoma in the United States, 2004-2016.

Gino Cioffi, Debra N Yeboa, Michael Kelly, Nirav Patil, Nauman Manzoor, Katie Greppin, Kailey Takaoka, Kristin Waite, Carol Kruchko, Jill S Barnholtz-Sloan

Open access · goldAbstract read
In one paragraph

Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  11. Observational
  12. Article
  13. Incidence of vestibular schwannoma in Finland, 1990-2017.Acta oncologica (Stockholm, Sweden) · 2024
    Article
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Gino CioffiDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Debra N YeboaDepartment of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Michael KellyDepartment of Pediatrics, Northeast Ohio Medical University, Rootstown, Ohio, USA.
Nirav PatilCentral Brain Tumor Registry of the United States, Hinsdale, Illinois, USA.
Nauman ManzoorEar Nose and Throat Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Katie GreppinHathaway Brown School, Shaker Heights, Ohio, USA.
Kailey TakaokaHathaway Brown School, Shaker Heights, Ohio, USA.
Kristin WaiteDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Carol KruchkoCentral Brain Tumor Registry of the United States, Hinsdale, Illinois, USA.
Jill S Barnholtz-SloanDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Central Brain Tumor Registry of the United States · USShaker Heights Public Library · USCase Comprehensive Cancer CenterCase Western Reserve University · USNortheast Ohio Medical University · USThe University of Texas MD Anderson Cancer Center · USUniversity Hospitals of Cleveland · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVestibular schwannomas (VS) are nonmalignant tumors of the eighth cranial nerve and are the most common nonmalignant nerve sheath tumor. This study provides the most comprehensive and current analysis of VS epidemiology in the United States.

methodsIncidence data were obtained from the Central Brain Tumor Registry of the United States, from 2004 to 2016 for VS. Age-adjusted incidence rates (AAIRs), rate ratios (AAIRRs), and prevalence ratios (AAPRs) per 100 000 were analyzed by age, sex, race and ethnicity, and laterality. Additional analyses were performed to assess differences in treatment, laterality, and diagnostic confirmation.

resultsIncidence of VS was highest among adults (aged 65-74 years, AAIR: 3.18, 95% confidence interval [CI]: 3.15-3.25). However, there was a much higher distribution of bilateral tumors compared to unilateral in children aged 0-19 years (28.5% vs 1.0%,

conclusionsVS incidence and prevalence are highest among adults and white non-Hispanics. Bilateral VS was more common among children. There was an increase of radiographically confirmed VS over time. A higher proportion of patients received surgical treatment than radiotherapy. Population-based statistics provide healthcare professionals with vital information regarding disease burden and help improve patient care.

Indexed as

brain tumorsCBTRUSepidemiologyvestibular schwannoma

Identifiers

PMID33241216
PMCPMC7672330
OpenAlexW3092168499

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.