Evidence map›Paper›PMID 33241212›Full record

ArticleBrain communications2020

Cerebellar neuromodulation improves naming in post-stroke aphasia.

Rajani Sebastian, Ji Hyun Kim, Rachel Brenowitz, Donna C Tippett, John E Desmond, Pablo A Celnik, Argye E Hillis

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Brain communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05093673 (Cerebellar Stimulation for Aphasia Rehabilitation), which is not on this map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05093673 narecruitingnot on this mapstarted 2021, after this paper: background citation

Cerebellar Stimulation for Aphasia Rehabilitation

TypeinterventionalSponsorJohns Hopkins UniversityRan2021 to 2028Enrolled60ConditionsStrokeArmsCathodal Cerebellar tDCS, Semantic Feature Analysis (SFA), Sham
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Rajani SebastianDepartment of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Ji Hyun KimDepartment of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-0927-3764
Rachel BrenowitzDepartment of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Donna C TippettDepartment of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
John E DesmondDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Pablo A CelnikDepartment of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Argye E HillisDepartment of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Johns Hopkins University · US

Funding

Telerehab for Aphasia (TERRA)P50DC014664 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI FRIDRIKSSON, JULIUS · 2016 to 2025
$25.0M
Cerebellar Transcranial Direct Current Stimulation to Augment Chronic Aphasia TreatmentR00DC015554 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI SEBASTIAN, RAJANI · 2018 to 2020
$720k
Cerebellar Transcranial Direct Current Stimulation to Augment Chronic Aphasia TreatmentK99DC015554 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI SEBASTIAN, RAJANI · 2016 to 2017
$176k
NIDCD NIH HHS K99 DC015554NIDCD NIH HHS P50 DC014664NIDCD NIH HHS R00 DC015554
6 · The paper itself

Abstract

Transcranial direct current stimulation has been shown to increase the efficiency of language therapy in chronic aphasia; however, to date, an optimal stimulation site has not been identified. We investigated whether neuromodulation of the right cerebellum can improve naming skills in chronic aphasia. Using a randomized, double-blind, sham-controlled, within-subject crossover study design, participants received anodal cerebellar stimulation (

Indexed as

aphasiacerebellumlanguage therapystroketranscranial direct current stimulation

Identifiers

PMID33241212
PMCPMC7677607
OpenAlexW3106763379

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.