Evidence map›Paper›PMID 33241086›Full record

ArticleGlobal pediatric health2020

Clinical Prognostic Factors in Pediatric Patients With Orthostatic Intolerance.

Kazue Ishitsuka, Kaori Yamawaki, Miwako Horikawa, Hisaya Nakadate, Akira Nagai, Akira Ishiguro

Open access · goldAbstract read
In one paragraph

Article in Global pediatric health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kazue IshitsukaNational Center for Child Health and Development, Tokyo, Japan.ORCID https://orcid.org/0000-0002-2944-7012
Kaori YamawakiNational Center for Child Health and Development, Tokyo, Japan.ORCID https://orcid.org/0000-0001-6759-2643
Miwako HorikawaNational Center for Child Health and Development, Tokyo, Japan.
Hisaya NakadateNational Center for Child Health and Development, Tokyo, Japan.
Akira NagaiNational Center for Child Health and Development, Tokyo, Japan.
Akira IshiguroNational Center for Child Health and Development, Tokyo, Japan.ORCID https://orcid.org/0000-0002-3896-5313
National Center For Child Health and Development · JPKyushu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Midodrine is widely used for orthostatic intolerance (OI); however, little is known about the prognostic factors of OI after midodrine treatment. We retrospectively reviewed electronic medical charts to investigate clinical prognostic factors of OI on 159 OI patients aged 7 to 18 years who were treated with midodrine at a children's hospital. Logistic regression was conducted to clarify predictors for improving symptoms at the first month of the treatment. Patients with orthostatic uncomfortable feeling or fainting were significantly more likely to improve symptoms at the first month of the treatment (odds ratio [OR], 3.48; 95% confidence interval [95%CI], 1.36-8.89), but patients with underweight were significantly less likely to improve symptoms (OR, 0.19; 95%CI, 0.06-0.56). Our results suggest that predictive factors for OI by midodrine treatments are orthostatic symptoms and underweight in pediatric patients. These findings are useful to develop further studies for OI treatments.

Indexed as

adolescentschildrenmidodrineorthostatic intoleranceprognostic factors

Identifiers

PMID33241086
PMCPMC7672775
OpenAlexW3100443007

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.