Evidence map›Paper›PMID 33241065›Full record

ArticleOpen forum infectious diseases2020

Prevalence and Factors Associated With Liver Fibrosis Among Adult HIV-Infected Patients Attending Urban and Rural Care Clinics in Uganda.

Clara Wekesa, Gregory D Kirk, Jim Aizire, Eve-Marie Benson, Alex Karabarinde, Rosalind Parkes-Ratanshi, Ponsiano Ocama

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Impact of Socio-Economic, Behavioural and Clinical Factors on Liver Disease Progression in Individuals With HIV and Hepatitis B.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Observational
  4. Article
  5. Article
  6. Article
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Clara WekesaMRC/UVRI and London School of Hygiene and Tropical Medicine Uganda Research, Entebbe, Uganda.ORCID 0000-0001-6064-237X
Gregory D KirkJohn Hopkins University, Baltimore, Maryland, USA.
Jim AizireJohn Hopkins University, Baltimore, Maryland, USA.
Eve-Marie BensonJohn Hopkins University, Baltimore, Maryland, USA.
Alex KarabarindeMRC/UVRI and London School of Hygiene and Tropical Medicine Uganda Research, Entebbe, Uganda.
Rosalind Parkes-RatanshiCambridge University, Institute of Public Health, Cambridge, UK.
Ponsiano OcamaHIV and HCC in Uganda (H2U) Consortium, Infectious Diseases Institute, Kampala, Uganda.
Johns Hopkins University · USInfectious Diseases Institute · UGUganda Virus Research Institute · UGUniversity of Cambridge · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundLiver fibrosis is common among HIV-infected patients. Risk factors vary by location. Understanding this variation may inform prevention strategies. We compared the prevalence and correlates of liver fibrosis among HIV-infected patients attending care clinics in Uganda.

methodsThis was a cross-sectional study involving 2030 HIV-infected patients attending care clinics in urban and rural Uganda. Liver fibrosis was defined as liver stiffness measurement (LSM) >7.1 KPa. Proportions and correlates of liver fibrosis were assessed and compared using logistic regression stratified by gender and site.

resultsPrevalence of liver fibrosis was higher among participants in the rural clinic (15% vs 11%;

conclusionsLiver fibrosis is prevalent among HIV-infected persons in Uganda. HIV viral suppression and avoiding tobacco may be strategies to prevent liver fibrosis and cancer risk.

Indexed as

ART eraFibroscanHIV/AIDSliver fibrosisSub-Saharan Africa

Identifiers

PMID33241065
PMCPMC7676506
OpenAlexW3107450184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.