Evidence map›Paper›PMID 33241056›Full record

ArticleInterspeech2018

Classification of Huntington Disease using Acoustic and Lexical Features.

Matthew Perez, Wenyu Jin, Duc Le, Noelle Carlozzi, Praveen Dayalu, Angela Roberts, Emily Mower Provost

Open access · greenAbstract read
In one paragraph

Article in Interspeech, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. An End-to-End Overview of Clinical Speech AI.IEEE transactions on audio, speech, and language processing (2025) · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Observational
  8. Article
  9. Article
  10. Understanding speech and swallowing difficulties in individuals with Huntington disease: Validation of the HDQLIFE Speech Difficulties and Swallowing Difficulties Item Banks.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
    Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Matthew PerezComputer Science and Engineering, University of Michigan, Ann Arbor, MI.
Wenyu JinComputer Science and Engineering, University of Michigan, Ann Arbor, MI.
Duc LeComputer Science and Engineering, University of Michigan, Ann Arbor, MI.
Noelle CarlozziPhysical Medicine & Rehabilitation, University of Michigan, Ann Arbor, MI.
Praveen DayaluMichigan Medicine, University of Michigan, Ann Arbor, MI.
Angela RobertsDepartment of Communication Sciences and Disorders, Northwestern University, Evanston, IL.
Emily Mower ProvostComputer Science and Engineering, University of Michigan, Ann Arbor, MI.
University of Michigan · USNorthwestern University · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Validation of the HD-HRQOL (Huntington disease quality of life measure)R01NS077946 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CARLOZZI, NOELLE E. · 2012 to 2016
$3.2M
NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1 TR002240NINDS NIH HHS R01 NS077946
6 · The paper itself

Abstract

Speech is a critical biomarker for Huntington Disease (HD), with changes in speech increasing in severity as the disease progresses. Speech analyses are currently conducted using either transcriptions created manually by trained professionals or using global rating scales. Manual transcription is both expensive and time-consuming and global rating scales may lack sufficient sensitivity and fidelity [1]. Ultimately, what is needed is an unobtrusive measure that can cheaply and continuously track disease progression. We present first steps towards the development of such a system, demonstrating the ability to automatically differentiate between healthy controls and individuals with HD using speech cues. The results provide evidence that objective analyses can be used to support clinical diagnoses, moving towards the tracking of symptomatology outside of laboratory and clinical environments.

Indexed as

clinical applicationHuntington diseasespeech analysisspeech feature extractionspeech recognition

Identifiers

PMID33241056
PMCPMC7685291
OpenAlexW2889195510

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.