ReviewAnnals of translational medicine2020
Approaches to quantify optical coherence tomography angiography metrics.
Review in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 43 citations in OpenAlex.
- A New Approach to Retinal Oxygen Extraction Measurement Based on Laser Speckle Flowgraphy and Retinal Oximetry.Translational vision science & technology · 2024Trial
- Macular Choriocapillaris and Retinal Microvascular Alterations Across the Prediabetes-Early Type 2 Diabetes Continuum.Investigative ophthalmology & visual science · 2026Article
- Vascular topological primitives resolve post-ischemic microvascular risk fields and enable early prediction in longitudinal OCTA.Biomedical optics express · 2026Article
- Effect of Optical Coherence Tomography Angiography Image Artifacts on Quantitation of Vessel Density and Perfusion.Ophthalmic surgery, lasers & imaging retina · 2026Article
- Local Versus Global Binarization Techniques After Frangi Filtering for Optical Coherence Tomography Angiography Based Retinal Vessel Density Assessment in Diabetic Retinopathy.Diagnostics (Basel, Switzerland) · 2026Article
- Evaluation of Deep Learning-Based OCTA Denoising in Retinal Vessel Assessment.Translational vision science & technology · 2025Article
- Comments on Xie et al.'s Study on Artificial Intelligence-Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy.Translational vision science & technology · 2025Article
- Retinal Microstructural and Microvascular Changes in Alzheimer Disease: A Review.International ophthalmology clinics · 2025Review
- Scan speed affects quantitative optical coherence tomography angiography vascular metrics.Scientific reports · 2024Article
- Factors Associated With Ocular Perfusion Measurements as Obtained With Laser Speckle Contrast Imaging.Translational vision science & technology · 2024Article
- Comparing Optical Coherence Tomography Angiography Metrics in Healthy Chinese and Caucasian Adults.Journal of personalized medicine · 2024Article
- Combining retinal and choroidal microvascular metrics improves discriminative power for diabetic retinopathy.The British journal of ophthalmology · 2023Article
- Quantitative Parameters Relevant for Diabetic Macular Edema Evaluation by Optical Coherence Tomography Angiography.Medicina (Kaunas, Lithuania) · 2023Review
- Localized transverse flow measurement with dynamic light scattering line-scan OCT.Biomedical optics express · 2023Article
- Microvascular changes in the macular and parafoveal areas of multiple sclerosis patients without optic neuritis.Scientific reports · 2022Article
- Towards standardizing retinal optical coherence tomography angiography: a review.Light, science & applications · 2022Review
- Relationship of Quantitative Retinal Capillary Network and Myocardial Remodeling in Systemic Hypertension.Journal of the American Heart Association · 2022Article
- The Development and Clinical Application of Innovative Optical Ophthalmic Imaging Techniques.Frontiers in medicine · 2022Review
- Short-term changes in retinal and choroidal relative flow volume after anti-VEGF treatment for neovascular age-related macular degeneration.Scientific reports · 2021Article
- Comparative study of optical coherence tomography angiography algorithms for rodent retinal imaging.Experimental biology and medicine (Maywood, N.J.) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Optical coherence tomography (OCT) has revolutionized the field of ophthalmology in the last three decades. As an OCT extension, OCT angiography (OCTA) utilizes a fast OCT system to detect motion contrast in ocular tissue and provides a three-dimensional representation of the ocular vasculature in a non-invasive, dye-free manner. The first OCT machine equipped with OCTA function was approved by U.S. Food and Drug Administration in 2016 and now it is widely applied in clinics. To date, numerous methods have been developed to aid OCTA interpretation and quantification. In this review, we focused on the workflow of OCTA-based interpretation, beginning from the generation of the OCTA images using signal decorrelation, which we divided into intensity-based, phase-based and phasor-based methods. We further discussed methods used to address image artifacts that are commonly observed in clinical settings, to the algorithms for image enhancement, binarization, and OCTA metrics extraction. We believe a better grasp of these technical aspects of OCTA will enhance the understanding of the technology and its potential application in disease diagnosis and management. Moreover, future studies will also explore the use of ocular OCTA as a window to link ocular vasculature to the function of other organs such as the kidney and brain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.