ReviewAnnals of translational medicine2020
Optical coherence tomography angiography in glaucoma.
Review in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 33 citations in OpenAlex.
- Subtype-Specific Macular Vascular Signatures in Primary Open-Angle, Pseudoexfoliative, and Normal-Tension Glaucoma: OCT Angiography Study.Medicina (Kaunas, Lithuania) · 2026Article
- APSified Peripapillary Vessel Density in Glaucoma Suspects and Open-Angle Glaucoma.Diagnostics (Basel, Switzerland) · 2026Article
- Cardiac Surgery Patients Have Reduced Vascularity and Structural Defects of the Retina Similar to Persons with Open-Angle Glaucoma.Diagnostics (Basel, Switzerland) · 2024Article
- The application of functional imaging in visual field defects: a brief review.Frontiers in neurology · 2024Review
- Commentary: Can the vessels help solve the puzzle? Distinguishing high myopes from primary open-angle glaucomas.Indian journal of ophthalmology · 2022Article
- Caveolar and non-Caveolar Caveolin-1 in ocular homeostasis and disease.Progress in retinal and eye research · 2022Review
- Spatial positional relationship between macular superficial vessel density and ganglion cell-inner plexiform layer thickness in primary angle closure glaucoma.International ophthalmology · 2022Article
- Exploring Ocular Perfusion and Structural Alterations of POAG in Indonesia: Insights from OCTA and OCT Analysis.Journal of current glaucoma practiceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Assessment of the vasculature within the optic nerve, peripapillary superficial retina, macula, and peripapillary choroid can be determined in glaucoma using optical coherence tomography angiography (OCTA). Decreased perfusion within the pre-laminar layer of the optic nerve has been correlated with glaucoma severity. The peripapillary superficial retinal vessel density allows diagnosis and detection of glaucoma progression in a manner similar to the peripapillary retinal nerve fiber layer (RNFL) thickness. Furthermore, decreased peripapillary vessel density of the intact hemiretina or unaffected eye of glaucomatous eyes suggests that vascular changes can occur prior to detectable visual field damage. The accuracy for glaucoma detection of the macular ganglion cell (MGC) thickness compared to macular vessel density has differed among studies. Several studies have reported reduction of macular vessel density as well as its ganglion cell thickness. Results of studies evaluating the parapapillary choroid have shown a greater prevalence of choroidal microvasculature dropout in glaucomatous eyes with a parapapillary gamma zone, which is associated with central visual field defects or glaucoma progression. It remains unclear whether the reduced vessel density in glaucoma is a primary event or secondary to glaucomatous damage. Further studies are warranted to elucidate this question.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.