Evidence map›Paper›PMID 33240795›Full record

ArticleBiotechnology reports (Amsterdam, Netherlands)2020

Synthesis and cytotoxic analysis of thiolated xylose derivatives decorated on gold nanoparticles.

Angus Shiue, Jenn-Han Chen, Chia-Ying Chang, Shu-Mei Chang, Kuo-Yuan Hwa, Kai-Yen Chin, Graham Leggett

Abstract read
In one paragraph

Article in Biotechnology reports (Amsterdam, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Angus ShiueGraduate Institute of Organic and Polymeric Materials, National Taipei University of Technology, Taipei, Taiwan.
Jenn-Han ChenGraduate Institute of Clinical Medicine, Taipei Medical University, Taipei, Taiwan.
Chia-Ying ChangGraduate Institute of Organic and Polymeric Materials, National Taipei University of Technology, Taipei, Taiwan.
Shu-Mei ChangGraduate Institute of Organic and Polymeric Materials, National Taipei University of Technology, Taipei, Taiwan.
Kuo-Yuan HwaGraduate Institute of Organic and Polymeric Materials, National Taipei University of Technology, Taipei, Taiwan.
Kai-Yen ChinGraduate Institute of Organic and Polymeric Materials, National Taipei University of Technology, Taipei, Taiwan.
Graham LeggettLI-COR Biosciences, Cambridge, England.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid development of metal nanoparticles capped by an organic monolayer offers the possibility to create a whole new variety of products with novel characteristic, functions and applications. Among these, nanoparticles covered with carbohydrates (glyconanoparticles) constitute a good bio-mimetic model of carbohydrate presentation at the cell surface and are currently centered on many glycobiological and biomedical applications. In this study, a series of novel D-xylose gold nanoparticles (AuNPs) with linkages of alkyl or polyethylene glycol have been synthesized via D-xylosethiols, forming self-assembled monolayers on gold nanoparticles. The nano-gold solution, two carbohydrate derivatives and modified nano-gold solution were tested for cytotoxicity to check the biocompatibility. The MTT assay on NIH 3T3 cell lines confirmed that all the test materials showed no toxicity with the more than 90 % of cell viability in both low concentration (1 μM) and high concentration (100 μM), compared with the control.

Indexed as

Gold nanoparticlesPlasmon resonanceSurfaceXylose

Identifiers

PMID33240795
PMCPMC7674290

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.