Evidence map›Paper›PMID 33240740›Full record

ArticleBiophysics and physicobiology2020

Rapid differentiation of human dental pulp stem cells to neuron-like cells by high K

Yuki Kogo, Chiaki Seto, Yuki Totani, Mai Mochizuki, Taka Nakahara, Kotaro Oka, Tohru Yoshioka, Etsuro Ito

Abstract read
In one paragraph

Article in Biophysics and physicobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  10. Influence of gap junctions upon CaBiophysics and physicobiology · 2022
    Article
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  12. Dorsolateral prefrontal cortex sensing analgesia.Biophysics and physicobiology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuki KogoDepartment of Biology, Waseda University, Tokyo 162-8480, Japan.
Chiaki SetoDepartment of Biology, Waseda University, Tokyo 162-8480, Japan.
Yuki TotaniDepartment of Biology, Waseda University, Tokyo 162-8480, Japan.
Mai MochizukiDepartment of Life Science Dentistry, The Nippon Dental University, Tokyo 102-8159, Japan.
Taka NakaharaDepartment of Developmental and Regenerative Dentistry, The Nippon Dental University School of Life Dentistry at Tokyo, Tokyo 102-8159, Japan.
Kotaro OkaDepartment of Bioscience and Informatics, Faculty of Science and Technology, Keio University, Yokohama 223-8522, Japan.
Tohru YoshiokaWaseda Research Institute for Science and Engineering, Waseda University, Tokyo 169-8555, Japan.
Etsuro ItoDepartment of Biology, Waseda University, Tokyo 162-8480, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As human-origin cells, human dental pulp stem cells (hDPSCs) are thought to be potentially useful for biological and medical experiments. They are easily obtained from lost primary teeth or extracted wisdom teeth, and they are mesenchymal stem cells that are known to differentiate into osteoblasts, chondrocytes, and adipocytes. Although hDPSCs originate from neural crest cells, it is difficult to induce hDPSCs to differentiate into neuron-like cells. To facilitate their differentiation into neuron-like cells, we evaluated various differentiation conditions. Activation of K

Indexed as

dental pulp stem cellhigh K+ stimulationneural differentiationneuron-like cell

Identifiers

PMID33240740
PMCPMC7671740

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.