Evidence map›Paper›PMID 33240692›Full record

ReviewCureus2020

Transdermal Nicotine as a Treatment Option for Ulcerative Colitis: A Review.

Vishmita Kannichamy, Ishan Antony, Vinayak Mishra, Amit Banerjee, Arohi B Gandhi, Ifrah Kaleem, Josh Alexander, Mohamed Hisbulla, Safeera Khan

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Phytochemicals derived fromFrontiers in pharmacology · 2024
    Review
  3. Article
  4. Effect of Nicotine on Immune System Function.Advanced pharmaceutical bulletin · 2023
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Vishmita KannichamyInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Ishan AntonyInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Vinayak MishraInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Amit BanerjeeInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Arohi B GandhiInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Ifrah KaleemInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Josh AlexanderGeneral Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Mohamed HisbullaInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Safeera KhanInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
California Institute of Behavioral Neurosciences and Psychology (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis (UC) is primarily a disease of non-smokers or ex-smokers. Since there have been previous claims of the beneficial effects of transdermal nicotine, researchers studied its efficacy to include it in the treatment regimen: to prevent remissions and as maintenance therapy. This review aims to evaluate the efficacy of transdermal nicotine as a treatment option for mild to moderately active ulcerative colitis. We shortlisted 22 articles after a careful analysis and elimination process. These articles were reviewed and analyzed, and it was found that transdermal nicotine in combination with conventional therapy was more beneficial than individual treatment with either. Further controlled studies evaluating the appropriate dosage for remission and maintenance treatment needs to be done.

Indexed as

inflammatory bowel diseasenicotineulcerative colitis (uc)

Identifiers

PMID33240692
PMCPMC7681756
OpenAlexW3094519112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.