ArticlePeerJ2020
Third molar agenesis in modern humans with and without agenesis of other teeth.
Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- AXIN2 variants, tooth agenesis, and cancer risk: a systematic review.BMC oral health · 2025Pooled it
- Association between unilateral third molar elongation, temporomandibular joint space asymmetry, and posterior tooth wear: a CBCT study.BMC oral health · 2026Article
- Association between third molar agenesis and dental maturity in Brazilian children.Forensic science, medicine, and pathology · 2026Article
- Third Molar Impaction Influence on Dental Estimation: A Systemic Review.Acta stomatologica Croatica · 2026Article
- Investigating a potential association between agenesis of the third molars and variations in dental crown dimensions.PloS one · 2026Article
- Dissecting the Genetic Contribution of Tooth Agenesis.International journal of molecular sciences · 2025Review
- Three-dimensional tooth morphology in patients with tooth agenesis and its association to agenesis pattern, severity, and sex.Scientific reports · 2025Article
- Risk factors for delayed-onset infection after lower third molar surgery: a retrospective case-control study.Oral and maxillofacial surgery · 2025Article
- Genetic Aspects of Tooth Agenesis.Genes · 2025Review
- Palatal canine impaction is not associated with third molar agenesis.European journal of orthodontics · 2025Article
- Long-Term Oro-Dental Effects of Chemotherapy in a Pediatric Patient: A Case Study and a Proposed Oral Care Protocol.Journal of clinical medicine · 2025Article
- Exploring the Association Between Third Molar Agenesis and Carabelli Traits: A Cross-Sectional Study.Dentistry journal · 2025Article
- Prevalence of congenital missing permanent teeth and its association with side and gender in a Saudi subpopulation.PloS one · 2025Article
- Oral Health Status and Treatment Needs Based on Artificial Intelligence (AI) Dental Panoramic Radiograph (DPR) Analysis: A Cross-Sectional Study.Journal of clinical medicine · 2024Article
- Occlusal characteristics in modern humans with tooth agenesis.Scientific reports · 2024Article
- Association between dental agenesis and facial morphology. A cross-sectional study in France.PloS one · 2024Observational
- Supernumerary Tooth Patterns in Non-Syndromic White European Subjects.Dentistry journal · 2023Article
- Article
- Forensic Age Estimation: A Multifactorial Approach in a Retrospective Population Study.Diagnostics (Basel, Switzerland) · 2023Article
- Odontostomatological Traits in North-Eastern Italy's Isolated Populations: An Epidemiological Cross-Sectional Study.Journal of clinical medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe number of teeth in the human dentition is of interest both from developmental and evolutionary aspects. The present case-control study focused on the formation of third molars in modern humans aiming to shed more light on the most variable tooth class in the dentition. MATERIALS AND
methodsFor this reason, we investigated third molar formation in a sample of 303 individuals with agenesis of teeth other than third molars (agenesis group) and compared it to a sex and age matched control group of 303 individuals without agenesis of teeth other than third molars.
resultsThe prevalence of third molar agenesis in the agenesis group was 50.8%, which is significantly higher than the 20.5% in the control group (
conclusionThe present results indicate that genetic factors involved in tooth agenesis affect also the dentition as a whole. Furthermore, the third molars are more vulnerable to factors involved in agenesis of other teeth and they are more often affected as a whole. These findings seem to be associated with the evolutionary trend in humans towards reduced molar number.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.