ArticleSouthern African journal of HIV medicine2020
Human immunodeficiency virus, diabetes mellitus and thyroid abnormalities: Should we be screening?
Article in Southern African journal of HIV medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- Thyroid disorders in patients with human immunodeficiency virus infection: a meta-analysis.AIDS research and therapy · 2025Pooled it
- A Contemporary Multifaceted Narrative Review on Thyroid Dysfunction in People Living with Human Immunodeficiency Virus.Biomedicines · 2025Review
- Prevalence of thyroid dysfunction in highly active antiretroviral therapy -Exposed people living with human immunodeficiency virus.Thyroid research · 2025Article
- Viral infection and thyroid disorders: a narrative review.Frontiers in microbiology · 2025Review
- Comorbidities in people living with HIV/AIDS and their impact on outpatient dental care.Brazilian oral research · 2025Observational
- A Literature Review on SARS-CoV-2 and Other Viruses in Thyroid Disorders: Environmental Triggers or No-Guilty Bystanders?International journal of environmental research and public health · 2023Review
- Changes in multimorbidity burden over a 3-5 year period among people with HIV.Frontiers in systems biology · 2023Article
- Thyroid Diseases and Thyroid Asymptomatic Dysfunction in People Living With HIV.Infectious disease reports · 2022Review
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetes mellitus (DM) and human immunodeficiency virus (HIV) are associated with thyroid abnormalities. Scarce literature exists on the prevalence of thyroid abnormalities in people living with HIV (PLWH) and DM (PLWHD). Guidelines vary regarding thyroid-stimulating hormone (TSH) screening in PLWH and/or DM.
objectivesThis study describes thyroid abnormalities in PLWHD and HIV-uninfected people living with DM (PLWD).
methodThis was a cross-sectional analysis of demographic, clinical and biochemical data including TSH results of first-visit patients to the Edendale Hospital diabetes clinic between January 2016 and December 2017.
resultsA total of 915 patients were enrolled: 165 PLWHD and 750 PLWD. Overall prevalence of thyroid disorders in PLWD was 8.53% (64/750). The occurrence of 'total' thyroid disorders and of 'subclinical-hypothyroidism' (SCH) was higher in PLWHD than PLWD (23.03% vs. 8.53% and 20.61% vs. 4%,
conclusionOur study showed an increased prevalence of thyroid disorders (especially SCH) in PLWD and a higher prevalence in PLWHD. Young, overweight, female PLWHD were at risk of SCH. People living with HIV and DM on ART demonstrated an increased prevalence of thyroid dysfunction and poor lipaemic control. The introduction of combined communicable-non-communicable disease clinics might provide an integrated patient screening option.
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