Evidence map›Paper›PMID 33240394›Full record

ArticleTherapeutic advances in gastroenterology2020

Characterization of fungal and bacterial dysbiosis in young adult Chinese patients with Crohn's disease.

Xinyun Qiu, Xiaojing Zhao, Xiufang Cui, Xiaqiong Mao, Nana Tang, Chunhua Jiao, Di Wang, Yue Zhang, Ziping Ye, Hongjie Zhang

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
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  11. The Gut Mycobiome for Precision Medicine.Journal of fungi (Basel, Switzerland) · 2025
    Review
  12. Gut fungal profile in new onset treatment-naïve ulcerative colitis in Saudi children.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Article
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  18. Role ofWorld journal of gastroenterology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xinyun QiuDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID https://orcid.org/0000-0001-6409-2408
Xiaojing ZhaoDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiufang CuiDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiaqiong MaoDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Nana TangDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Chunhua JiaoDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Di WangDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yue ZhangDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ziping YeDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Hongjie ZhangDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300#, Nanjing, 210029, China.
Jiangsu Province Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal microbiota dysbiosis has been described in inflammatory bowel disease (IBD), but data from China are limited. In this study, we performed molecular analysis of the fecal microbial community from 20 healthy Chinese subjects and 25 patients with Crohn's disease (CD), and evaluated associations with bacterial and fungal compositions. Decreased richness and diversity of bacterial composition was observed in the CD group compared with healthy (H) subjects. Significant structural differences in bacterial (but not fungal) composition among healthy controls and CD patients were found. A reduction in Firmicutes and Actinobacteria abundance, and overrepresentation of Proteobacteria were observed in the CD patients compared with the H group. The

Indexed as

bacteriaCrohn’s diseasefungiinflammatory bowel diseaseintestinal microbiota

Identifiers

PMID33240394
PMCPMC7672770
OpenAlexW3099178832

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.