Evidence map›Paper›PMID 33240323›Full record

ArticleFrontiers in genetics2020

CD52 Is a Prognostic Biomarker and Associated With Tumor Microenvironment in Breast Cancer.

Jianxin Wang, Guangchen Zhang, Yang Sui, Zhuowen Yang, Yinzhu Chu, Hailing Tang, Binbin Guo, Cong Zhang, Changjun Wu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 51 citations in OpenAlex.

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  14. Single cell sequencing of the mouse anterior palate reveals mesenchymal heterogeneity.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jianxin WangDepartment of Ultrasound, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Guangchen ZhangDepartment of Ultrasound, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Yang SuiDepartment of Ultrasound, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Zhuowen YangDepartment of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Yinzhu ChuDepartment of Ultrasound, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Hailing TangDepartment of Ultrasound, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Binbin GuoDepartment of Ultrasound, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Cong ZhangDepartment of Ultrasound, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Changjun WuDepartment of Ultrasound, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Harbin Medical University · CNFirst Affiliated Hospital of Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor microenvironment (TME) plays an essential role in the development and metastasis of breast cancer (BC). More studies are needed on the differences and functions of immune components and matrix components. In this study, we calculated the proportion of tumor-infiltrating immune cells (TICs) and the proportion of immune and matrix components of BC patients from The Cancer Genome Atlas (TCGA). We performed Cox regression analysis and constructed protein-protein interaction (PPI) network based on the differentially expressed genes (DEGs) and obtained the most crucial gene

Indexed as

breast cancerCD52immune infiltrationprognosistumor microenvironment

Identifiers

PMID33240323
PMCPMC7667128
OpenAlexW3096411814

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.