Evidence map›Paper›PMID 33240286›Full record

ArticleFrontiers in immunology2020

IL-1β-MyD88-mTOR Axis Promotes Immune-Protective IL-17A

Natarajan Bhaskaran, Fady Faddoul, Andre Paes da Silva, Sangeetha Jayaraman, Elizabeth Schneider, Prerna Mamileti, Aaron Weinberg, Pushpa Pandiyan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  5. Enrichment ofFrontiers in immunology · 2026
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  19. Limonin Inhibits IL-1Oxidative medicine and cellular longevity · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Natarajan BhaskaranDepartment of Biological Sciences, Case Western Reserve University, Cleveland, OH, United States.
Fady FaddoulAdvanced Education in General Dentistry, Case Western Reserve University, Cleveland, OH, United States.
Andre Paes da SilvaDepartment of Periodontics, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
Sangeetha JayaramanDepartment of Biological Sciences, Case Western Reserve University, Cleveland, OH, United States.
Elizabeth SchneiderDepartment of Biological Sciences, Case Western Reserve University, Cleveland, OH, United States.
Prerna MamiletiDepartment of Biological Sciences, Case Western Reserve University, Cleveland, OH, United States.
Aaron WeinbergDepartment of Biological Sciences, Case Western Reserve University, Cleveland, OH, United States.
Pushpa PandiyanDepartment of Biological Sciences, Case Western Reserve University, Cleveland, OH, United States.
Case Western Reserve University · US

Funding

WG3: HIV, Co-infections and Co-morbiditiesP30AI036219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI Alan David Levine · 1994 to 2026
$50.0M
METABOLOME ANALYSES OF SALIVA SAMPLES FROM HIV+ PATIENTS ON cARTR01DE026923 · NIDCR · CASE WESTERN RESERVE UNIVERSITY · PI Pushpa Pandiyan · 2017 to 2026
$4.5M
NIAID NIH HHS P30 AI036219NIDCR NIH HHS R01 DE026923
6 · The paper itself

Abstract

CD4

Indexed as

Signal TransductionAge FactorsAgingAnimalsBiomarkersCytokinesDisease SusceptibilityImmunohistochemistryImmunophenotypingInterleukin-1betaMiceMucous MembraneMyeloid Differentiation Factor 88StomatitisT-Lymphocytes, RegulatoryTOR Serine-Threonine KinasesBiomarkersCytokinesInterleukin-1betaMyeloid Differentiation Factor 88TOR Serine-Threonine KinasesagingCandidaFoxp3fungal infectionIL-1βsenescenceTregTreg17

Identifiers

PMID33240286
PMCPMC7677307
OpenAlexW3095704885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.