Evidence map›Paper›PMID 33240277›Full record

ArticleFrontiers in immunology2020

Alzheimer's Disease-Like Pathology Triggered by

Jaime Díaz-Zúñiga, Jamileth More, Samanta Melgar-Rodríguez, Matías Jiménez-Unión, Francisca Villalobos-Orchard, Constanza Muñoz-Manríquez, Gustavo Monasterio, José Luis Valdés, Rolando Vernal, Andrea Paula-Lima

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 3 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Coinfection ofFrontiers in immunology · 2026
    Article
  14. Association between Alzheimer's disease andWorld journal of biological chemistry · 2025
    Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Alzheimer's Disease andLife (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jaime Díaz-ZúñigaPeriodontal Biology Laboratory, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
Jamileth MoreCentro de Investigación Clínica Avanzada (CICA), Hospital Clínico Universidad de Chile, Santiago, Chile.
Samanta Melgar-RodríguezPeriodontal Biology Laboratory, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
Matías Jiménez-UniónPeriodontal Biology Laboratory, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
Francisca Villalobos-OrchardPeriodontal Biology Laboratory, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
Constanza Muñoz-ManríquezPeriodontal Biology Laboratory, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
Gustavo MonasterioPeriodontal Biology Laboratory, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
José Luis ValdésBiomedical Neuroscience Institute, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Rolando VernalPeriodontal Biology Laboratory, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
Andrea Paula-LimaBiomedical Neuroscience Institute, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
University of Chile · CLHospital Clínico de la Universidad de Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal disease is a disease of tooth-supporting tissues. It is a chronic disease with inflammatory nature and infectious etiology produced by a dysbiotic subgingival microbiota that colonizes the gingivodental sulcus. Among several periodontal bacteria,

Indexed as

Alzheimer DiseaseBacteroidaceae InfectionsPeriodontitisPorphyromonas gingivalisAnimalsBone ResorptionCytokinesHippocampusLearningLipid PeroxidationMaleRats, Sprague-DawleySerogroupThiobarbituric Acid Reactive SubstancesCytokinesThiobarbituric Acid Reactive SubstancesAlzheimer’s diseasegliamemoryneuroinflammationperiodontitis

Identifiers

PMID33240277
PMCPMC7680957
OpenAlexW3100416080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.