Evidence map›Paper›PMID 33240267›Full record

ReviewFrontiers in immunology2020

Targeting the PD-1/PD-L1 Axis in Human Vitiligo.

Marcella Willemsen, Cornelis J M Melief, Marcel W Bekkenk, Rosalie M Luiten

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Implication of Immunobiological Function of Melanocytes in Dermatology.Clinical reviews in allergy & immunology · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Hair Graying Regulators Beyond Hair Follicle.Frontiers in physiology · 2022
    Article
  14. Article
  15. Translational Research in Vitiligo.Frontiers in immunology · 2021
    Review
  16. Recent Advances in Management of Vitiligo.Indian journal of dermatology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Marcella WillemsenDepartment of Dermatology and Netherlands Institute for Pigment Disorders, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Cancer Center Amsterdam, Amsterdam Infection & Immunity Institute, Amsterdam, Netherlands.
Cornelis J M MeliefISA Pharmaceuticals, Leiden, Netherlands.
Marcel W BekkenkDepartment of Dermatology and Netherlands Institute for Pigment Disorders, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Cancer Center Amsterdam, Amsterdam Infection & Immunity Institute, Amsterdam, Netherlands.
Rosalie M LuitenDepartment of Dermatology and Netherlands Institute for Pigment Disorders, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Cancer Center Amsterdam, Amsterdam Infection & Immunity Institute, Amsterdam, Netherlands.
Amsterdam University Medical Centers · NLISA Pharmaceuticals (Netherlands) · NLUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoreactive CD8

Indexed as

AnimalsAutoimmunityB7-H1 AntigenCD8-Positive T-LymphocytesHumansImmune Checkpoint InhibitorsMelanocytesMolecular Targeted TherapyProgrammed Cell Death 1 ReceptorSignal TransductionSkinSkin PigmentationVitiligoB7-H1 AntigenCD274 protein, humanImmune Checkpoint InhibitorsPDCD1 protein, humanProgrammed Cell Death 1 ReceptorautoimmunityB7-H1 antigenimmune toleranceprogrammed cell death 1 receptorvitiligo

Identifiers

PMID33240267
PMCPMC7677560
OpenAlexW3097909863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.