Evidence map›Paper›PMID 33240219›Full record

ArticleFrontiers in endocrinology2020

Inhibition of Y1 Receptor Promotes Osteogenesis in Bone Marrow Stromal Cells

Wei Yu, Fan-Cheng Chen, Wen-Ning Xu, Sheng-Long Ding, Peng-Bo Chen, Lei Yang, Sheng-Dan Jiang, Xiao-Yun Pan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Article
  5. Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Wei YuDepartment of Orthopaedic Surgery, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Fan-Cheng ChenShanghai Medical College, Fudan University, Shanghai, China.
Wen-Ning XuDepartment of Clinic of Spine Center, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Sheng-Long DingDepartment of Orthopaedic, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, China.
Peng-Bo ChenDepartment of Clinic of Spine Center, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Lei YangDepartment of Orthopaedic Surgery, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Sheng-Dan JiangDepartment of Clinic of Spine Center, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Xiao-Yun PanDepartment of Orthopaedic Surgery, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
XinHua Hospital · CNFudan University · CNSecond Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University · CNShanghai Medical College of Fudan University · CNWenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhibition of neuropeptide Y1 receptor stimulates osteogenesis

Indexed as

OsteogenesisAdultApoptosisBiomarkersCell ProliferationCells, CulturedCore Binding Factor Alpha 1 SubunitCyclic AMPCyclic AMP-Dependent Protein KinasesCyclic AMP Response Element-Binding ProteinFemaleGene Expression RegulationHumansMaleMesenchymal Stem CellsReceptors, Neuropeptide YBiomarkersCore Binding Factor Alpha 1 SubunitCREB1 protein, humanCyclic AMPCyclic AMP-Dependent Protein KinasesCyclic AMP Response Element-Binding ProteinReceptors, Neuropeptide YRNA, Small InterferingRUNX2 protein, humanbone marrow stromal cells (BMSCs)neuropeptide Y1 receptorosteogenesisprotein kinase ARUNX2

Identifiers

PMID33240219
PMCPMC7683715
OpenAlexW3103670890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.