ReviewFrontiers in neurology2020
Neural Correlates of Freezing of Gait in Parkinson's Disease: An Electrophysiology Mini-Review.
Review in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Cerebellar tDCS combined with augmented reality treadmill for freezing of gait in Parkinson's disease: a randomized controlled trial.Journal of neuroengineering and rehabilitation · 2024Trial
- Frequency-Specific EEG burst dynamics in Parkinson's Disease and freezing of gait.Journal of neurology · 2026Article
- Cerebellar Electrical Activity as a Marker for Predicting Brain Health and Disease: A Review.Brain sciences · 2026Review
- Is levodopa induced freezing of gait a paradox or an expected phenomenon?: a clinico-pathophysiological hypothesis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Review
- Task-specific dynamical entropy variations in EEG as a biomarker for Parkinson's disease progression.GeroScience · 2026Article
- Deep neurobehavioral phenotyping uncovers neural fingerprints of locomotor deficits in Parkinson's disease.NPJ Parkinson's disease · 2026Article
- Freezing of gait and the effects of vibrotactile cueing in Parkinson's disease-a study protocol of a cross-sectional multimodal brain imaging approach in virtual walking scenarios.Frontiers in neuroscience · 2026Article
- Identifying gait characteristics associated with freezing of gait in Parkinson's disease: An analysis of on and off medication states.Gait & posture · 2025Article
- Personalized versus fixed tactile cueing in Parkinson's disease: Protocol for a randomized controlled trial on gait automaticity.PloS one · 2025Article
- NOTCH2NLC GGC intermediate repeat with serine induces hypermyelination and early Parkinson's disease-like phenotypes in mice.Molecular neurodegeneration · 2024Article
- Directional Subthalamic Deep Brain Stimulation Better Improves Gait and Balance Disorders in Parkinson's Disease Patients: A Randomized Controlled Study.Annals of neurology · 2024Article
- Efficacy of exercise interventions combined with Selegiline in ameliorating freezing of gait in Parkinson's disease patients.American journal of translational research · 2024Article
- Comparing the efficacy of therapeutic Thai acupressure on plantar acupoints and laser cane therapy on freezing of gait in Parkinson's disease: a randomized non-inferiority trial.Frontiers in neurology · 2024Article
- Associations of ambient manganese exposure with brain gray matter thickness and white matter hyperintensities.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Supplementary Motor Area Activity Differs in Parkinson's Disease with and without Freezing of Gait.Parkinson's disease · 2023Article
- Residual effects of combined vibratory and plantar stimulation while seated influences plantar pressure and spatiotemporal gait measures in individuals with Parkinson's disease exhibiting freezing of gait.Frontiers in aging neuroscience · 2023Article
- Allocation of cognitive resources in cognitive processing of rhythmic visual stimuli before gait-related motor initiation.Frontiers in neuroscience · 2023Article
- Characterizing neurocognitive impairments in Parkinson's disease with mobile EEG when walking and stepping over obstacles.Brain communications · 2023Article
- Association between Severity of Freezing of Gait and Turning Characteristics in People with Parkinson's Disease.International journal of environmental research and public health · 2022Article
- Abnormal neural oscillations during gait and dual-task in Parkinson's disease.Frontiers in systems neuroscience · 2022Review
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
Abstract
Freezing of gait (FoG) is a disabling symptom characterized as a brief inability to step or by short steps, which occurs when initiating gait or while turning, affecting over half the population with advanced Parkinson's disease (PD). Several non-competing hypotheses have been proposed to explain the pathophysiology and mechanism behind FoG. Yet, due to the complexity of FoG and the lack of a complete understanding of its mechanism, no clear consensus has been reached on the best treatment options. Moreover, most studies that aim to explore neural biomarkers of FoG have been limited to semi-static or imagined paradigms. One of the biggest unmet needs in the field is the identification of reliable biomarkers that can be construed from real walking scenarios to guide better treatments and validate medical and therapeutic interventions. Advances in neural electrophysiology exploration, including EEG and DBS, will allow for pathophysiology research on more real-to-life scenarios for better FoG biomarker identification and validation. The major aim of this review is to highlight the most up-to-date studies that explain the mechanisms underlying FoG through electrophysiology explorations. The latest methodological approaches used in the neurophysiological study of FoG are summarized, and potential future research directions are discussed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.