Evidence map›Paper›PMID 33240129›Full record

ArticleFrontiers in psychiatry2020

Social Frailty in the COVID-19 Pandemic Era.

Madia Lozupone, Maddalena La Montagna, Ilaria Di Gioia, Rodolfo Sardone, Emanuela Resta, Antonio Daniele, Gianluigi Giannelli, Antonello Bellomo, Francesco Panza

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

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  6. Evaluating Policies to Decrease the Risk of Introducing SARS-CoV-2 Infections to Nursing Home Facilities.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Madia LozuponeNeurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy.
Maddalena La MontagnaPsychiatric Unit, Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Ilaria Di GioiaPsychiatric Unit, Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Rodolfo SardonePopulation Health Unit - "Salus in Apulia Study" - National Institute of Gastroenterology "Saverio de Bellis," Research Hospital, Bari, Italy.
Emanuela RestaDepartment of Cardiac, Thoracic, and Vascular Science, Institute of Respiratory Disease, University of Bari Aldo Moro, Bari, Italy.
Antonio DanieleInstitute of Neurology, Catholic University of Sacred Heart, Rome, Italy.
Gianluigi GiannelliPopulation Health Unit - "Salus in Apulia Study" - National Institute of Gastroenterology "Saverio de Bellis," Research Hospital, Bari, Italy.
Antonello BellomoPsychiatric Unit, Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Francesco PanzaPopulation Health Unit - "Salus in Apulia Study" - National Institute of Gastroenterology "Saverio de Bellis," Research Hospital, Bari, Italy.
University of Foggia · ITGastroenterology Hospital "Saverio de Bellis" · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Special attention and efforts to protect from or reduce health-related outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus triggering coronavirus disease 2019 (COVID-19), should be applied in susceptible populations, including frail older people. In particular, the early death cases occurred primarily in older people with a frailty status, possibly due to a weaker immune system fostering faster progression of the viral infection. Frailty is an age-related multidimensional clinical condition defined as a non-specific state of vulnerability, identifying older people at increased risk of falls, institutionalization, hospitalization, disability, dementia, and death. Among frailty phenotypes, social frailty has been least studied. It considers the role of socioeconomic context as a vulnerability status later in life. COVID-19 does not affect all populations equally, and social inequalities contribute to drive the spread of infections. It was known that the perception of social isolation, e.g., loneliness, affects mental and physical health, but the implicated molecular mechanisms, also related to the immune system, and its associated cognitive and health-related sequelae, are poorly understood. The increasing psychological distress derived by prolonged exposure to stress due to the lockdown scenario, and the reduced sources of support, contributed to making heavy demands on personal resources, i.e., self-efficacy and interpersonal variables. So, perceived loneliness may be a factor associated with psychological distress and an outcome in itself. In the COVID-19 pandemic era, a correct assessment of social frailty may be essential in terms of the prevention of late-life neuropsychiatric disorders.

Indexed as

biomarkerscoronavirusimmune systemLate-Life Depression (LLD)lonelinessMultimorbidity (MM)SARS-CoV-2social dysfunction

Identifiers

PMID33240129
PMCPMC7669751
OpenAlexW3095261714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.