Evidence map›Paper›PMID 33240117›Full record

ArticleFrontiers in psychiatry2020

Neural Correlates of Theory of Mind in Autism Spectrum Disorder, Attention-Deficit/Hyperactivity Disorder, and the Comorbid Condition.

Daniel Ilzarbe, Steve Lukito, Carolin Moessnang, Owen G O'Daly, David J Lythgoe, Clodagh M Murphy, Karen Ashwood, Vladimira Stoencheva, Katya Rubia, Emily Simonoff

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 3 countries.

Daniel IlzarbeDepartment of Child and Adolescent Psychiatry, King's College London (KCL), Institute of Psychiatry, Psychology and Neuroscience (IoPPN), London, United Kingdom.
Steve LukitoDepartment of Child and Adolescent Psychiatry, King's College London (KCL), Institute of Psychiatry, Psychology and Neuroscience (IoPPN), London, United Kingdom.
Carolin MoessnangDepartment of Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, Mannheim, Germany.
Owen G O'DalyCentre for Neuroimaging Sciences, King's College London, London, United Kingdom.
David J LythgoeCentre for Neuroimaging Sciences, King's College London, London, United Kingdom.
Clodagh M MurphyBehavioural and Developmental Psychiatry Clinical Academic Group, Behavioural Genetics Clinic, Adult Autism and Attention Deficit Hyperactivity Disorder Service, South London and Maudsley NHS Foundation Trust, London, United Kingdom.
Karen AshwoodBehavioural and Developmental Psychiatry Clinical Academic Group, Behavioural Genetics Clinic, Adult Autism and Attention Deficit Hyperactivity Disorder Service, South London and Maudsley NHS Foundation Trust, London, United Kingdom.
Vladimira StoenchevaBehavioural and Developmental Psychiatry Clinical Academic Group, Behavioural Genetics Clinic, Adult Autism and Attention Deficit Hyperactivity Disorder Service, South London and Maudsley NHS Foundation Trust, London, United Kingdom.
Katya RubiaDepartment of Child and Adolescent Psychiatry, King's College London (KCL), Institute of Psychiatry, Psychology and Neuroscience (IoPPN), London, United Kingdom.
Emily SimonoffDepartment of Child and Adolescent Psychiatry, King's College London (KCL), Institute of Psychiatry, Psychology and Neuroscience (IoPPN), London, United Kingdom.
King's College London · GBCentral Institute of Mental Health · DE

Funding

Medical Research Council MR/P012647/1
6 · The paper itself

Abstract

Theory of mind (ToM) or mentalizing difficulties is reported in attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), but the mechanism underpinning these apparently shared deficits is relatively unknown. Eighty-three young adult males, 19 with ASD alone, 21 with ADHD alone, 18 with dual diagnosis of ASD and ADHD, and 25 typically developing (TD) controls completed the functional magnetic resonance imaging version of the Frith-Happé animated-triangle ToM task. We compared neural function during ToM with two non-ToM conditions, random and goal directed motions, using whole-brain and region-of-interest analysis of brain activation and functional connectivity analyses. The groups showed comparable ToM task performance. All three clinical groups lacked local connectivity increase shown by TD controls during ToM in the right temporoparietal cortex, a key mentalizing region, with a differentially

Indexed as

attention deficit and hyperactivity disorder (ADHD)autism spectrum disoder (ASD)functional magnetic resonance imaging (fMRI)neurodevelopmental disordertheory of mind (ToM)

Identifiers

PMID33240117
PMCPMC7677232
OpenAlexW3062208440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.