Evidence map›Paper›PMID 33240089›Full record

ArticleFrontiers in pharmacology2020

Evodiamine Attenuates Experimental Colitis Injury Via Activating Autophagy and Inhibiting NLRP3 Inflammasome Assembly.

Wenwen Ding, Zhiquan Ding, Yong Wang, Yan Zhu, Qi Gao, Wangsen Cao, Ronghui Du

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wenwen DingJiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing, China.
Zhiquan DingJiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing, China.
Yong WangJiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing, China.
Yan ZhuJiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing, China.
Qi GaoJiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing, China.
Wangsen CaoJiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing, China.
Ronghui DuJiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing, China.
Nanjing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy and NLRP3 inflammasome were associated with the process of colitis. Drugs targeting NLRP3 inflammasome and autophagy to treat colitis are absent, and they are urgently required. Herein, we examine the effect of evodiamine, extracted from the fruit of

Indexed as

ASCautophagycolitisevodiamineNLRP3 inflammasome

Identifiers

PMID33240089
PMCPMC7681073
OpenAlexW3104835992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.