Evidence map›Paper›PMID 33240077›Full record

ArticleFrontiers in aging neuroscience2020

The Effects of a Wearable Sensory Prosthesis on Gait and Balance Function After 10 Weeks of Use in Persons With Peripheral Neuropathy and High Fall Risk - The walk2Wellness Trial.

Lars I E Oddsson, Teresa Bisson, Helen S Cohen, Laura Jacobs, Mohammad Khoshnoodi, Doris Kung, Lewis A Lipsitz, Brad Manor, Patricia McCracken, Yvonne Rumsey and 2 more

3 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03538756 nacompletednot on this map

walk2Wellness: Long-term Use Effects of Walkasins® Wearable Sensory Prosthesis on Gait Function, Balance-Confidence, and Social Participation

TypeinterventionalSponsorRxFunction Inc.Ran2018 to 2021Enrolled69ConditionsSensory Peripheral Neuropathy, Balance, Distorted, Sensation DisordersArmsWalkasins
NCT06959277 narecruitingnot on this mapstarted 2025, after this paper: background citation

Balance4Mobility: Effects of Walkasins Use on Clinical Outcomes of Gait and Balance Function in Individuals With Peripheral Neuropathy and Balance Problems - A Randomized Control Trial

TypeinterventionalSponsorRxFunction Inc.Ran2025 to 2027Enrolled200ConditionsPeripheral Neuropathies, Peripheral Neuropathy Due to Chemotherapy, Peripheral Neuropathy With Type 2 Diabetes, Balance Control in ElderlyArmsWalkasins, Fall Prevention Training
NCT07554443 narecruitingnot on this mapstarted 2026, after this paper: background citation

Wearable Sensory Prostheses to Improve Neuromuscular Coordination, Walking Function, and Real-World Physical Activity

TypeinterventionalSponsorRxFunction Inc.Ran2026 to 2027Enrolled18ConditionsPeripheral Neuropathy With Type 2 Diabetes, Peripheral Neuropathy Grade 2 or Greater, Balance, Balance Impairment, Gait Disorders, FatigueArmsExternal, lower limb sensory prosthesis
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  3. Article
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  6. Wearable Technologies Using Peripheral Neuromodulation to Enhance Mobility and Gait Function in Older Adults-A Narrative Review.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 2 countries.

Lars I E OddssonRxFunction Inc., Eden Prairie, MN, United States.
Teresa BissonDepartment of Rehabilitation Medicine, University of Minnesota, Minneapolis, MN, United States.
Helen S CohenBaylor College of Medicine, Houston, TX, United States.
Laura JacobsRxFunction Inc., Eden Prairie, MN, United States.
Mohammad KhoshnoodiThe Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Doris KungBaylor College of Medicine, Houston, TX, United States.
Lewis A LipsitzHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Roslindale, MA, United States.
Brad ManorHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Roslindale, MA, United States.
Patricia McCrackenMinneapolis VA Health Care System, Minneapolis, MN, United States.
Yvonne RumseyRxFunction Inc., Eden Prairie, MN, United States.
Diane M WrisleyCollege of Saint Mary, Omaha, NE, United States.
Sara R Koehler-McNicholasDepartment of Rehabilitation Medicine, University of Minnesota, Minneapolis, MN, United States.
RxFunction (United States) · USBaylor College of Medicine · USCollege of Saint Mary · USFairview Health Services · USHarvard University · USHebrew SeniorLife · USJohns Hopkins University · USMinneapolis VA Health Care System · USUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSensory peripheral neuropathy (PN) is associated with gait, balance problems and high fall risk. The walk2Wellness trial investigates effects of long-term, home-based daily use of a wearable sensory prosthesis on gait function, balance, quality of life and fall rates in PN patients. The device (Walkasins

methodsParticipants had PN with lost plantar sensation, gait and balance problems, an FGA score < 23 (high fall risk), and ability to sense tactile stimuli above the ankle. Clinical outcomes included FGA, Gait Speed, Timed Up&Go (TUG) and 4-Stage Balance Test. Patient-reported outcomes included Activities-Specific Balance Confidence (ABC) scale, Vestibular Disorders Activities of Daily Living Scale, PROMIS participation and satisfaction scores, pain rating, and falls. Evaluations were performed at baseline and after 2, 6, and 10 weeks. Subjects were not made aware of changes in outcomes. No additional balance interventions were allowed.

resultsForty-five participants of 52 enrolled across four sites completed in-clinic assessments. FGA scores improved from 15.0 to 19.1 (

conclusionA wearable sensory prosthesis presents a new way to treat gait and balance problems and manage falls in high fall-risk patients with PN.

trial registrationClinicalTrials.gov (#NCT03538756).

Indexed as

balancefallsgait speedneuromodulationneuroprosthesisperipheral neuropathysensory prosthesissensory substitution

Identifiers

PMID33240077
PMCPMC7680959
OpenAlexW3100163914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.