Evidence map›Paper›PMID 33240076›Full record

SynthesisFrontiers in aging neuroscience2020

Characterization of EEG Data Revealing Relationships With Cognitive and Motor Symptoms in Parkinson's Disease: A Systematic Review.

Qing Wang, Lin Meng, Jun Pang, Xiaodong Zhu, Dong Ming

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in aging neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qing WangAcademy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Lin MengAcademy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Jun PangAcademy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Xiaodong ZhuDepartment of Neurology, Tianjin Medical University General Hospital, Tianjin, China.
Dong MingAcademy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent research regards the electroencephalogram (EEG) as a promising method to study real-time brain dynamic changes in patients with Parkinson's disease (PD), but a deeper understanding is needed to discern coincident pathophysiology, patterns of changes, and diagnosis. This review summarized recent research on EEG characterization related to the cognitive and motor functions in PD patients and discussed its potential to be used as diagnostic biomarkers. Thirty papers out of 220 published from 2010 to 2020 were reviewed. Movement abnormalities and cognitive decline are related to changes in EEG spectrum and event-related potentials (ERPs) during typical oddball paradigms and/or combined motor tasks. Abnormalities in β and δ frequency bands are, respectively the main manifestation of dyskinesia and cognitive decline in PD. The review showed that PD patients have noteworthy changes in specific EEG characterizations, however, the underlying mechanism of the interrelation between gait and cognitive is still unclear. Understanding the specific nature of the relationship is essential for development of novel invasive clinical diagnostic and therapeutic methods.

Indexed as

cognitive declinedementiaelectroencephalogram (EEG)freezing of gait (FOG)motor disordersParkinson's disease (PD)

Identifiers

PMID33240076
PMCPMC7683572

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.