Evidence map›Paper›PMID 33240018›Full record

ArticlePostepy dermatologii i alergologii2020

Evaluation of the effects of hair colouring products on the oxidative status in rats.

Hülya Nazik, Duygun Altintaş Aykan, Muhammed Seyithanoğlu, Perihan Öztürk, Mehmet Kamil Mülayim, Hakan Nazik

Open access · goldAbstract read
In one paragraph

Article in Postepy dermatologii i alergologii, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hülya NazikDepartment of Dermatology, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Turkey.
Duygun Altintaş AykanDepartment of Pharmacology, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Turkey.
Muhammed SeyithanoğluDepartment of Biochemistry, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Turkey.
Perihan ÖztürkDepartment of Dermatology, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Turkey.
Mehmet Kamil MülayimDepartment of Dermatology, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Turkey.
Hakan NazikDepartment of Obstetrics and Gynecology, Adana Numune Education and Research Hospital, Adana, Turkey.
Kahramanmaraş Sütçü İmam University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPermanent hair dyes, oxidant creams, and henna are usually used for cosmetic purposes and sometimes for therapeutic expectations. The effects of these products, which are used to change hair colour and can be absorbed percutaneously on the oxidative status is not known exactly.

aimTo investigate the effects of these products, which have various contents, on the oxidative status using an MATERIAL AND

methodsThe products used for hair colouring were prepared as recommended for human use and applied to the back region of Wistar albino rats. Superoxide dismutase (SOD), malondialdehyde (MDA) and glutathione peroxidase (GSH-Px) levels were measured in serum and liver samples of rats. The Kruskal-Wallis test showed significant differences in serum SOD, aspartate aminotranspherase (AST), alanine aminotranspherase (ALT), and liver MDA levels among the study groups.

resultsThere were statistically significant positive correlations between hepatic MDA values and AST and ALT values. Hair dyes, oxidant creams, and henna were found to have oxidative and hepatotoxic effects. Surprisingly, comparisons revealed that oxidative effect and hepatic toxicity of the oxidant cream and henna were similar. The oxidant cream was more oxidating and hepatotoxic than the hair dye.

conclusionsKnowing the facts about these products, which are easily accessible to every individual in society and are considered to be innocent, will prevent possible harm.

Indexed as

hair dyehennahepatotoxicityoxidant creamoxidative stress

Identifiers

PMID33240018
PMCPMC7675090
OpenAlexW3107769169

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.