Evidence map›Paper›PMID 33239928›Full record

ArticleRisk management and healthcare policy2020

Effect of Pandemic-Related Confinement on Vitamin D Status Among Children Aged 0-6 Years in Guangzhou, China: A Cross-Sectional Study.

Li Yu, Hai-Jin Ke, Di Che, Shao-Lan Luo, Yong Guo, Jie-Ling Wu

Open access · goldAbstract read
In one paragraph

Article in Risk management and healthcare policy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Effect of the COVID-19 Pandemic on Serum Vitamin D Levels in People Under Age 18 Years: A Systematic Review and Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2022
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  10. COVID-19 in Children and Vitamin D.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Li YuDepartment of Children's Health Care, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.
Hai-Jin KeDepartment of Children's Health Care, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.
Di CheDepartment of Children's Health Care, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.
Shao-Lan LuoDepartment of Children's Health Care, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.
Yong GuoDepartment of Children's Health Care, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.
Jie-Ling WuDepartment of Children's Health Care, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.
Guangdong Province Women and Children Hospital · CNGuangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePandemic-related confinement helps to contain the transmission of the novel coronavirus disease (COVID-19) but restricts children's exposure to sunlight, thereby possibly affecting their 25-hydroxyvitamin D [25(OH)D] levels. This study aimed to examine the effect of COVID-19 measures on 25(OH)D levels in children. PATIENTS AND

methodsThis study included children who underwent health checks between March 1 and June 30, 2020, and those over the equivalent period during 2017-2019 (N = 3600). Children's 25(OH)D levels and the proportion of children with vitamin D deficiency were compared between different observation periods.

resultsThe mean serum 25(OH)D level was 84 ± 25nmol/L. The overall proportion of children with vitamin D deficiency (25(OH)D level <50 nmol/L) was 4.6%. Home confinement led to an increase in the proportion of children aged 3-6 years with vitamin D deficiency during March 1-June 30, 2020 compared with the same months in previous years, and the most noticeable increase was found in March 2020. In children aged 3-6 years, 25(OH)D levels were lower in 2020 (65 ± 17nmol/L) than during 2017-2019, and the proportion of those with vitamin D deficiency was higher in 2020 (19.0%) than in previous years. Among children aged 0.5-1 and 1-3 years, 25(OH)D levels were higher (97 ± 25 nmol/L, 91 ± 27 nmol/L), while the proportion of children with vitamin D deficiency was lower in 2020 (2.3%, 3.0%) than during 2017-2019.

conclusionThe 25(OH)D levels tended to decrease gradually with increasing age. Reduced sunlight exposure during confinement is associated with lower 25(OH)D levels among children aged 3-6 years. Therefore, vitamin D supplementation for children aged >3 years is recommended.

Indexed as

25-hydroxyvitamin Dcoronavirus diseasedeficiencysunlight exposure

Identifiers

PMID33239928
PMCPMC7682604
OpenAlexW3103699603

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.