Evidence map›Paper›PMID 33239697›Full record

ArticleScientific reports2020

Combinations of modifiable lifestyle behaviours in relation to colorectal cancer risk in Alberta's Tomorrow Project.

Dylan E O'Sullivan, Amy Metcalfe, Troy W R Hillier, Will D King, Sangmin Lee, Joy Pader, Darren R Brenner

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. A Latent Class Analysis of Health Lifestyles in Relation to Suicidality among Adolescents in Mauritius.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Dylan E O'SullivanDepartment of Public Health Sciences, Queen's University, Kingston, ON, Canada.
Amy MetcalfeDepartment of Community Health Sciences, University of Calgary, Calgary, AB, Canada.
Troy W R HillierDepartment of Public Health Sciences, Queen's University, Kingston, ON, Canada.
Will D KingDepartment of Public Health Sciences, Queen's University, Kingston, ON, Canada.
Sangmin LeeDepartment of Community Health Sciences, University of Calgary, Calgary, AB, Canada.
Joy PaderDepartment of Cancer Epidemiology and Prevention Research, CancerControl Alberta, Alberta Health Services, Holy Cross Centre - Room 513C, Box ACB, 2210-2nd St. SW, Calgary, AB, T2S 3C3, Canada.
Darren R BrennerDepartment of Community Health Sciences, University of Calgary, Calgary, AB, Canada. Darren.Brenner@ucalgary.ca.
Queen's University · CAUniversity of Calgary · CAAlberta Health Services · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to identify distinct clusters of individuals that exhibit unique patterns of modifiable lifestyle-related behaviours and to determine how these patterns are associated with the risk of developing colorectal cancer (CRC). The study consisted of 26,460 participants and 267 CRC cases from Alberta's Tomorrow Project. Exploratory latent class analysis of risk behaviours (obesity, physical inactivity, meat consumption, smoking, alcohol consumption, and fruit and vegetable consumption) and Cox proportional hazard models were utilized. Seven unique behavioural groups were identified, where the risk of CRC was 2.34 to 2.87 times greater for high risk groups compared to the low risk group. Sex-specific models identified higher risk groups among men (Hazard Ratios [HRs]: 3.15 to 3.89) than among women (HRs: 1.99 to 2.19). Targeting groups defined by clustering of behaviours could potentially lead to more effective prevention of CRC on a population level.

Indexed as

Risk Reduction BehaviorAdultAlbertaColorectal NeoplasmsFemaleHealth BehaviorHumansLife StyleMaleMiddle AgedProportional Hazards ModelsRisk FactorsRisk-TakingSurveys and Questionnaires

Identifiers

PMID33239697
PMCPMC7689485
OpenAlexW3110571194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.