Evidence map›Paper›PMID 33239652›Full record

ArticleCommunications biology2020

Differences in visually induced MEG oscillations reflect differences in deep cortical layer activity.

Dimitris A Pinotsis, Earl K Miller

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Categorization is 'baked' into the brain.Nature reviews. Neuroscience · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Dimitris A PinotsisCentre for Mathematical Neuroscience and Psychology and Department of Psychology, City -University of London, London, EC1V 0HB, UK. pinotsis@mit.edu.ORCID 0000-0002-6865-8103
Earl K MillerThe Picower Institute for Learning & Memory and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Massachusetts Institute of Technology · USMcGovern Institute for Brain Research · US

Funding

Cortical Circuits for Attention and DecisionsR37MH087027 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI MILLER, EARL K · 2010 to 2019
$4.7M
NIMH NIH HHS R37MH087027
6 · The paper itself

Abstract

Neural activity is organized at multiple scales, ranging from the cellular to the whole brain level. Connecting neural dynamics at different scales is important for understanding brain pathology. Neurological diseases and disorders arise from interactions between factors that are expressed in multiple scales. Here, we suggest a new way to link microscopic and macroscopic dynamics through combinations of computational models. This exploits results from statistical decision theory and Bayesian inference. To validate our approach, we used two independent MEG datasets. In both, we found that variability in visually induced oscillations recorded from different people in simple visual perception tasks resulted from differences in the level of inhibition specific to deep cortical layers. This suggests differences in feedback to sensory areas and each subject's hypotheses about sensations due to differences in their prior experience. Our approach provides a new link between non-invasive brain imaging data, laminar dynamics and top-down control.

Indexed as

MagnetoencephalographyModels, NeurologicalBayes TheoremCerebral CortexHumansNerve NetSynapsesVisual Perception

Identifiers

PMID33239652
PMCPMC7688644
OpenAlexW3108178890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.