ArticleNature communications2020
A versatile and customizable low-cost 3D-printed open standard for microscopic imaging.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 170 citations in OpenAlex.
- Motilitometer: A compact modular microscope for motility and photoresponse analysis of microorganisms.HardwareX · 2026Article
- Single-Molecule Forster Resonance Energy Transfer With a Minimalistic 3D-Printed Setup and Dyes in the Blue-Green Spectral Region.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026Article
- Article
- Altair-LSFM A High-Resolution, Easy-to-Build Light-Sheet Microscope for Sub-Cellular Imaging.bioRxiv : the preprint server for biology · 2025Article
- Open Raman Microscopy (ORM): A Modular Hardware and Software Framework for Accessible Raman Imaging.bioRxiv : the preprint server for biology · 2025Article
- AI-assisted cervical cytology precancerous screening for high-risk population in resource-limited regions using a compact microscope.Nature communications · 2025Article
- Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology.Lab on a chip · 2025Article
- A 3D-printed optical microscope for low-cost histological imaging.Journal of microscopy · 2025Article
- Imaging 3D cell cultures with optical microscopy.Nature methods · 2025Review
- Fully automated multicolour structured illumination module for super-resolution microscopy with two excitation colours.Communications engineering · 2025Article
- 3D printed miniature attenuated total internal reflection assisted fluorescence microscopy.Scientific reports · 2025Article
- A low-cost platform for automated cervical cytology: addressing health and socioeconomic challenges in low-resource settings.Frontiers in medical technology · 2025Article
- zIncubascope: Long-term quantitative imaging of multi-cellular assemblies inside an incubator.PloS one · 2025Article
- VS-FPM: Large-Format, Label-Free Virtual Histopathology Microscopy.BME frontiers · 2025Article
- Open Photonics: An integrated approach for building a 3D-printed motorized rotation stage system.HardwareX · 2024Article
- Video-rate two-photon microendoscopy using second harmonic resonance fiber scanning.Biomedical optics express · 2024Article
- An open-source combined atomic force microscope and optical microscope for mechanobiology studies.Heliyon · 2024Article
- Single-molecule detection and super-resolution imaging with a portable and adaptable 3D-printed microscopy platform (Brick-MIC).Science advances · 2024Article
- Article
- Using old laboratory equipment with modern Web-of-Things standards: a smart laboratory with LabThings Retro.Royal Society open science · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Modern microscopes used for biological imaging often present themselves as black boxes whose precise operating principle remains unknown, and whose optical resolution and price seem to be in inverse proportion to each other. With UC2 (You. See. Too.) we present a low-cost, 3D-printed, open-source, modular microscopy toolbox and demonstrate its versatility by realizing a complete microscope development cycle from concept to experimental phase. The self-contained incubator-enclosed brightfield microscope monitors monocyte to macrophage cell differentiation for seven days at cellular resolution level (e.g. 2 μm). Furthermore, by including very few additional components, the geometry is transferred into a 400 Euro light sheet fluorescence microscope for volumetric observations of a transgenic Zebrafish expressing green fluorescent protein (GFP). With this, we aim to establish an open standard in optics to facilitate interfacing with various complementary platforms. By making the content and comprehensive documentation publicly available, the systems presented here lend themselves to easy and straightforward replications, modifications, and extensions.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.