Evidence map›Paper›PMID 33239373›Full record

ArticleJournal of clinical microbiology2021

Serum-Based Diagnosis of Pediatric Tuberculosis by Assay of Mycobacterium tuberculosis Factors: a Retrospective Cohort Study.

Yifan He, Christopher J Lyon, Duc T Nguyen, Chang Liu, Wei Sha, Edward A Graviss, Tony Y Hu

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Yifan HeDepartment of Biochemistry and Molecular Biology Center for Cellular and Molecular Diagnosis, School of Medicine, Tulane University, New Orleans, Louisiana, USA.
Christopher J LyonDepartment of Biochemistry and Molecular Biology Center for Cellular and Molecular Diagnosis, School of Medicine, Tulane University, New Orleans, Louisiana, USA.
Duc T NguyenDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, Texas, USA.
Chang LiuDepartment of Chemical Engineering, Biomedical Engineering Program, College of Engineering and Computing, University of South Carolina, Columbia, South Carolina, USA.
Wei ShaDepartment of Biochemistry and Molecular Biology Center for Cellular and Molecular Diagnosis, School of Medicine, Tulane University, New Orleans, Louisiana, USA.
Edward A GravissDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, Texas, USA.
Tony Y HuDepartment of Biochemistry and Molecular Biology Center for Cellular and Molecular Diagnosis, School of Medicine, Tulane University, New Orleans, Louisiana, USA TonyHu@tulane.edu.ORCID 0000-0001-7255-5409
Tulane University · USHouston Methodist · USUniversity of South Carolina · US

Funding

Direct quantitation of the circulating Mtb-peptidome for pediatric TB managementR01HD090927 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI Christopher J Lyon, Charles DeBeaux Mitchell · 2017 to 2026
$4.5M
SUPPORT MYCOBACTERIUM TUBERCULOSIS RESEARCH PROGRAMSN01AO002738 · AO · BAYLOR COLLEGE OF MEDICINE · PI GRAVISS, EDWARD A · 2000 to 2000
$3.3M
A nanopore biosensor for leveling Mtb antigens in bloodR01AI144168 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI Christopher J Lyon · 2022 to 2026
$3.0M
Quantification of Circulating Antigens for Pediatric TB Diagnosis andTreatment MonitoringR01AI122932 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI HU, TONY Y. · 2016 to 2019
$1.8M
Real-time Detection of Active TB in HIV Exposed Children on CustomizedNanotrapR01AI113725 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI LABAER, JOSHUA · 2015 to 2018
$1.6M
Multiplexed quantification of circulating peptidomic signatures for EBOLA early diagnosisR21AI126361 · NIAID · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI LABAER, JOSHUA · 2017 to 2018
$373k
Mobile based Nanoplasmonic Quantification of Mtb-derived Exosomes in Serum for Pediatric TB diagnosisR21EB026347 · NIBIB · TULANE UNIVERSITY OF LOUISIANA · PI LYON, CHRISTOPHER J · 2019 to 2020
$367k
NIAID NIH HHS N01 AO002738NIAID NIH HHS R01 AI113725NIAID NIH HHS R01 AI122932NIAID NIH HHS R01 AI144168NIAID NIH HHS R21 AI126361NIBIB NIH HHS R21 EB026347NICHD NIH HHS R01 HD090927
6 · The paper itself

Abstract

Diagnosis of pediatric tuberculosis (TB) is often complicated by its nonspecific symptoms, paucibacillary nature, and the need for invasive specimen collection techniques. However, a recently reported assay that detects

Indexed as

Mycobacterium tuberculosisTuberculosisAdultChildHumansProspective StudiesRetrospective StudiesSensitivity and Specificityextrapulmonary TBNanodisk-MSpediatric TBserum-based assay

Identifiers

PMID33239373
PMCPMC8111146
OpenAlexW3107393480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.