Evidence map›Paper›PMID 33239367›Full record

ArticlemSphere2020

Combinatorial Biosynthesis of Sulfated Benzenediol Lactones with a Phenolic Sulfotransferase from Fusarium graminearum PH-1.

Linan Xie, Dongliang Xiao, Xiaojing Wang, Chen Wang, Jing Bai, Qun Yue, Haitao Yue, Ye Li, István Molnár, Yuquan Xu and 1 more

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The divergence of DHN-derived melanin pathways in Metarhizium robertsii.World journal of microbiology & biotechnology · 2024
    Article
  5. Review
  6. Biosynthesis of Cytosporones in Leotiomycetous Filamentous Fungi.Journal of the American Chemical Society · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Microbial Conjugation Studies of Licochalcones and Xanthohumol.International journal of molecular sciences · 2021
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Linan Xie *Biotechnology Research Institute, The Chinese Academy of Agricultural Sciences, Beijing, People's Republic of China.
Dongliang Xiao *Biotechnology Research Institute, The Chinese Academy of Agricultural Sciences, Beijing, People's Republic of China.
Xiaojing Wang *Southwest Center for Natural Products Research, University of Arizona, Tucson, Arizona, USA.
Chen WangBiotechnology Research Institute, The Chinese Academy of Agricultural Sciences, Beijing, People's Republic of China.
Jing BaiBiotechnology Research Institute, The Chinese Academy of Agricultural Sciences, Beijing, People's Republic of China.
Qun YueBiotechnology Research Institute, The Chinese Academy of Agricultural Sciences, Beijing, People's Republic of China.
Haitao YueDepartment of Biology and Biotechnology, Xinjiang University, Urumqi, People's Republic of China.
Ye LiSouthwest Center for Natural Products Research, University of Arizona, Tucson, Arizona, USA.
István MolnárSouthwest Center for Natural Products Research, University of Arizona, Tucson, Arizona, USA imolnar@email.arizona.edu xuyuquan@caas.cn zhangliwen@caas.cn.ORCID 0000-0002-3627-0454
Yuquan XuBiotechnology Research Institute, The Chinese Academy of Agricultural Sciences, Beijing, People's Republic of China imolnar@email.arizona.edu xuyuquan@caas.cn zhangliwen@caas.cn.
Liwen ZhangBiotechnology Research Institute, The Chinese Academy of Agricultural Sciences, Beijing, People's Republic of China imolnar@email.arizona.edu xuyuquan@caas.cn zhangliwen@caas.cn.ORCID 0000-0003-1593-2778
Chinese Academy of Agricultural Sciences · CNUniversity of Arizona · USJiangnan University · CNSuzhou University of Science and Technology · CNXinjiang University · CN

Funding

Combinatorial biosynthesis of fungal benzenediol lactone polyketidesR01GM114418 · NIGMS · UNIVERSITY OF ARIZONA · PI MOLNAR, ISTVAN · 2016 to 2019
$1.4M
NIGMS NIH HHS R01 GM114418
6 · The paper itself

Abstract

Total biosynthesis or whole-cell biocatalytic production of sulfated small molecules relies on the discovery and implementation of appropriate sulfotransferase enzymes. Although fungi are prominent biocatalysts and have been used to sulfate drug-like phenolics, no gene encoding a sulfotransferase enzyme has been functionally characterized from these organisms. Here, we identify a phenolic sulfotransferase, FgSULT1, by genome mining from the plant-pathogenic fungus

Indexed as

AnimalsCell Line, TumorChlorocebus aethiopsFungal ProteinsFusariumHumansMutagenesis, Site-DirectedSulfotransferasesVero CellsFungal ProteinsSulfotransferasescombinatorial biosynthesisFusariumphenolic sulfotransferase

Identifiers

PMID33239367
PMCPMC7690957
OpenAlexW3107124442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.