Evidence map›Paper›PMID 33239342›Full record

ArticleGut2021

Semih Can Akıncılar, Lele Wu, Qin Feng Ng, Joelle Yi Heng Chua, Bilal Unal, Taichi Noda, Wei Hong Jeff Chor, Masahito Ikawa, Vinay Tergaonkar

Open access · hybridAbstract read
In one paragraph

Article in Gut, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Posttranscriptional Regulation of Intestinal Mucosal Growth and Adaptation by Noncoding RNAs in Critical Surgical Disorders.Journal of investigative surgery : the official journal of the Academy of Surgical Research · 2024
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  14. Review
  15. Review
  16. Macrophage polarization in inflammatory bowel disease.Cell communication and signaling : CCS · 2023
    Review
  17. Review
  18. Article
  19. Signaling pathways and targeted therapies for psoriasis.Signal transduction and targeted therapy · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Semih Can Akıncılar *Laboratory of NFκB Signalling, Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Institute of Molecular and Cell Biology, Singapore.ORCID 0000-0001-7588-2771
Lele Wu *Laboratory of NFκB Signalling, Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Institute of Molecular and Cell Biology, Singapore.ORCID 0000-0001-8333-226X
Qin Feng NgLaboratory of NFκB Signalling, Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Institute of Molecular and Cell Biology, Singapore.
Joelle Yi Heng ChuaLaboratory of NFκB Signalling, Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Institute of Molecular and Cell Biology, Singapore.
Bilal UnalLaboratory of NFκB Signalling, Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Institute of Molecular and Cell Biology, Singapore.
Taichi NodaResearch Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Wei Hong Jeff ChorLaboratory of NFκB Signalling, Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Institute of Molecular and Cell Biology, Singapore.
Masahito IkawaResearch Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Vinay TergaonkarLaboratory of NFκB Signalling, Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Institute of Molecular and Cell Biology, Singapore vinayt@imcb.a-star.edu.sg.
Agency for Science, Technology and Research · SGThe University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNFκB is the key modulator in inflammatory disorders. However, the key regulators that activate, fine-tune or shut off NFκB activity in inflammatory conditions are poorly understood. In this study, we aim to investigate the roles that NFκB-specific long non-coding RNAs (lncRNAs) play in regulating inflammatory networks.

designUsing the first genetic-screen to identify NFκB-specific lncRNAs, we performed RNA-seq from the

results

conclusion

Indexed as

AnimalsBiomarkersColitisDisease ProgressionFibroblastsHumansMAP Kinase Signaling SystemMiceProtein Phosphatase 2CRNA, Long NoncodingTranscription Factor RelABiomarkersPPM1D protein, humanPpm1d protein, mouseProtein Phosphatase 2CRNA, Long NoncodingTranscription Factor RelAchronic ulcerative colitisinflammationinflammatory bowel disease

Identifiers

PMID33239342
PMCPMC8458091
OpenAlexW3107368927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.