Evidence map›Paper›PMID 33239122›Full record

ReviewInfection control and hospital epidemiology2021

Pediatric research priorities in healthcare-associated infections and antimicrobial stewardship.

Susan E Coffin, Francisca Abanyie, Kristina Bryant, Joseph Cantey, Anthony Fiore, Stephanie Fritz, Judith Guzman-Cottrill, Adam L Hersh, W Charles Huskins, Larry K Kociolek and 21 more

Abstract readReview
In one paragraph

Review in Infection control and hospital epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 20 institutions in 1 country.

Susan E CoffinDivision of Infectious Diseases and Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Francisca AbanyieCenters for Disease Control and Prevention, Atlanta, Georgia.
Kristina BryantKosair Children's Hospital, University of Louisville School of Medicine, Louisville, Kentucky.
Joseph CanteyUniversity of Texas Health, San Antonio, Texas.
Anthony FioreCenters for Disease Control and Prevention, Atlanta, Georgia.
Stephanie FritzWashington University School of Medicine in St Louis, St Louis, Missouri.
Judith Guzman-CottrillDoernbecher Children's Hospital; Oregon Health & Science University, Portland, Oregon.
Adam L HershDepartment of Pediatrics, Division of Infectious Diseases, University of Utah, Salt Lake City, Utah.
W Charles HuskinsMayo Clinic College of Medicine, Rochester, Minnesota.
Larry K KociolekAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
Matthew KronmanSeattle Children's Hospital; University of Washington, Seattle, Washington.
Ebbing LautenbachPerelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Grace LeeStanford Children's Hospital; Stanford University School of Medicine, Palo Alto, California.
Matthew LinamChildren's Healthcare of Atlanta; Emory University School of Medicine, Atlanta, Georgia.
Latania K LoganRush University Medical Center; Rush Medical College, Chicago, Illinois.
Aaron MilstoneJohns Hopkins University School of Medicine, Baltimore, Maryland.
Jason NewlandWashington University School of Medicine in St Louis, St Louis, Missouri.
A Christine NyquistChildren's Hospital Colorado; University of Colorado School of Medicine, Aurora, Colorado.
Debra L PalazziTexas Children's Hospital: Baylor College of Medicine, Houston, Texas.
Sameer PatelAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
Karen PuopoloDivision of Infectious Diseases and Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Sujan C ReddyCenters for Disease Control and Prevention, Atlanta, Georgia.
Lisa SaimanNew York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, New York.
Thomas SandoraBoston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Andi L ShaneChildren's Healthcare of Atlanta; Emory University School of Medicine, Atlanta, Georgia.
Michael SmithDuke Children's Health Center; Duke University Medical Center, Durham, North Carolina.
Pranita D TammaJohns Hopkins University School of Medicine, Baltimore, Maryland.
Theoklis ZaoutisDivision of Infectious Diseases and Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Danielle ZerrSeattle Children's Hospital; University of Washington, Seattle, Washington.
Jeffrey S GerberDivision of Infectious Diseases and Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.ORCID 0000-0002-3076-3186
CDC Prevention Epicenters Program
Children's Hospital of Philadelphia · USCenters for Disease Control and Prevention · USEmory University · USJohns Hopkins University · USLurie Children's Hospital · USSeattle Children's Hospital · USBaylor College of Medicine · USBoston Children's Hospital · USChildren's Hospital Colorado · USDuke Medical Center · USLucile Packard Children's Hospital · USMayo Clinic · USNewYork–Presbyterian Hospital · USOregon Health & Science University · USRush University Medical Center · USSt. Louis Children's Hospital · USThe University of Texas Health Science Center at San Antonio · USUniversity of Louisville · USUniversity of Pennsylvania · USUniversity of Utah · US

Funding

Eliminating CLABSIs in Ambulatory PatientsR01HS022870 · AHRQ · JOHNS HOPKINS UNIVERSITY · PI MILSTONE, AARON M · 2014 to 2017
$1.5M
Intramural CDC HHS CC999999
6 · The paper itself

Abstract

objectiveTo develop a pediatric research agenda focused on pediatric healthcare-associated infections and antimicrobial stewardship topics that will yield the highest impact on child health.

participantsThe study included 26 geographically diverse adult and pediatric infectious diseases clinicians with expertise in healthcare-associated infection prevention and/or antimicrobial stewardship (topic identification and ranking of priorities), as well as members of the Division of Healthcare Quality and Promotion at the Centers for Disease Control and Prevention (topic identification).

methodsUsing a modified Delphi approach, expert recommendations were generated through an iterative process for identifying pediatric research priorities in healthcare associated infection prevention and antimicrobial stewardship. The multistep, 7-month process included a literature review, interactive teleconferences, web-based surveys, and 2 in-person meetings.

resultsA final list of 12 high-priority research topics were generated in the 2 domains. High-priority healthcare-associated infection topics included judicious testing for Clostridioides difficile infection, chlorhexidine (CHG) bathing, measuring and preventing hospital-onset bloodstream infection rates, surgical site infection prevention, surveillance and prevention of multidrug resistant gram-negative rod infections. Antimicrobial stewardship topics included β-lactam allergy de-labeling, judicious use of perioperative antibiotics, intravenous to oral conversion of antimicrobial therapy, developing a patient-level "harm index" for antibiotic exposure, and benchmarking and or peer comparison of antibiotic use for common inpatient conditions.

conclusionsWe identified 6 healthcare-associated infection topics and 6 antimicrobial stewardship topics as potentially high-impact targets for pediatric research.

Indexed as

Antimicrobial StewardshipClostridium InfectionsCross InfectionAdultAnti-Bacterial AgentsChildDelivery of Health CareHumansResearchAnti-Bacterial Agents

Identifiers

PMID33239122
PMCPMC13618984
OpenAlexW3109126177

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.