Observational studyWorld journal of emergency surgery : WJES2020
Comparison of qSOFA score, SOFA score, and SIRS criteria for the prediction of infection and mortality among surgical intermediate and intensive care patients.
Observational study in World journal of emergency surgery : WJES, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparing the Predictive Value of SOFA and SIRS for Mortality in the Early Hours of Hospitalization of Sepsis Patients: A Systematic Review and Meta-analysis.Archives of Iranian medicine · 2024Pooled it
- Recent advances in the biosensing platforms for sepsis diagnosis.RSC advances · 2026Review
- Diagnostic Value of End-Tidal Carbon Dioxide Combined With Lactate for Early Detection of Sepsis in Prehospital Patients: A Prospective Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- C-reactive Protein-Albumin-Lymphocyte (CALLY) Index in Patients With Sepsis: An Observational Study.Cureus · 2026Article
- Acute pancreatitis: mechanisms and therapeutic approaches.Signal transduction and targeted therapy · 2026Review
- Predictive Value of the Combination of Lactate and qSOFA Score for Clinical Outcomes in Cirrhotic Patients with Esophagogastric Variceal Bleeding.International journal of general medicine · 2026Article
- Prognostic value of low-cost white blood cell indices and procalcitonin for mortality in Rwandan sepsis patients: a prospective intensive care unit study.Tropical medicine and health · 2025Article
- Reduction of resources with mRNA host-response whole blood testing on patients presenting to the emergency department with suspected infections: a retrospective analysis of 30 cases.Journal of medical microbiology · 2025Article
- Development and validation of an explainable machine learning model for predicting prognosis in sepsis patients with a history of cancer who were admitted to the intensive care unit.The Journal of international medical research · 2025Article
- Associations between metabolomic scores and clinical outcomes in hospitalized COVID-19 patients.GeroScience · 2025Article
- Evaluation of physiological severity scores for predicting COVID-19 disease progression: a retrospective study.BMC infectious diseases · 2025Article
- Predicting ICU Mortality Among Septic Patients Using Machine Learning Technique.Journal of clinical medicine · 2025Article
- Construction and verification of a nomogram model for the risk of death in sepsis patients.Scientific reports · 2025Article
- Impact of trauma level designation on mortality in trauma patients with sepsis: an observational study across US trauma centers.Frontiers in medicine · 2025Article
- An optimal antibiotic selection framework for Sepsis patients using Artificial Intelligence.NPJ digital medicine · 2024Article
- Development and validation of a predictive model for in-hospital mortality from perioperative bacteremia in gastrointestinal surgery.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024Article
- Tools for Screening, Predicting, and Evaluating Sepsis and Septic Shock: A Comprehensive Review.Cureus · 2024Review
- Probable Non-Ventilator-Associated Hospital-Acquired Pneumonia: A Case Report.Critical care nurse · 2024Article
- Diagnosis and Therapy of Community-Acquired Pneumonia in the Emergency Department: A Retrospective Observational Study and Medical Audit.Journal of clinical medicine · 2024Article
- L-valine derived from the gut microbiota protects sepsis-induced intestinal injury and negatively correlates with the severity of sepsis.Frontiers in immunology · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is crucial to rapidly identify sepsis so that adequate treatment may be initiated. Accordingly, the Sequential Organ Failure Assessment (SOFA) and the quick SOFA (qSOFA) scores are used to evaluate intensive care unit (ICU) and non-ICU patients, respectively. As demand for ICU beds rises, the intermediate care unit (IMCU) carries greater importance as a bridge between the ICU and the regular ward. This study aimed to examine the ability of SOFA and qSOFA scores to predict suspected infection and mortality in IMCU patients.
methodsRetrospective data analysis included 13,780 surgical patients treated at the IMCU, ICU, or both between January 01, 2012, and September 30, 2018. Patients were screened for suspected infection (i.e., the commencement of broad-spectrum antibiotics) and then evaluated for the SOFA score, qSOFA score, and the 1992 defined systemic inflammatory response syndrome (SIRS) criteria.
resultsSuspected infection was detected in 1306 (18.3%) of IMCU, 1365 (35.5%) of ICU, and 1734 (62.0%) of IMCU/ICU encounters. Overall, 458 (3.3%) patients died (IMCU 45 [0.6%]; ICU 250 [6.5%]; IMCU/ICU 163 [5.8%]). All investigated scores failed to predict suspected infection independently of the analyzed subgroup. Regarding mortality prediction, the qSOFA score performed sufficiently within the IMCU cohort (AUCROC SIRS 0.72 [0.71-0.72]; SOFA 0.52 [0.51-0.53]; qSOFA 0.82 [0.79-0.84]), while the SOFA score was predictive in patients of the IMCU/ICU cohort (AUCROC SIRS 0.54 [0.53-0.54]; SOFA 0.73 [0.70-0.77]; qSOFA 0.59 [0.58-0.59]).
conclusionsNone of the assessed scores was sufficiently able to predict suspected infection in surgical ICU or IMCU patients. While the qSOFA score is appropriate for mortality prediction in IMCU patients, SOFA score prediction quality is increased in critically ill patients.
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