ArticleCritical care (London, England)2020
Individualized flow-controlled ventilation compared to best clinical practice pressure-controlled ventilation: a prospective randomized porcine study.
Article in Critical care (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 36 citations in OpenAlex.
- Computational tools for personalizing treatment of acute respiratory failure, from machine learning to digital twins: a narrative review.Critical care (London, England) · 2026Review
- Continuous-flow ventilation with VENTIJET in moderate ARDS: a pilot safety and feasibility study.Intensive care medicine experimental · 2026Article
- Flow-controlled ventilation versus pressure-controlled ventilation in moderate to severe ARDS patients: a randomized crossover physiological study.Intensive care medicine experimental · 2025Article
- Prolonged Flow-Controlled Ventilation in a Patient With ARDS and Multiple Trauma: A Case Report.Chest · 2025Article
- Negative end-expiratory versus zero end-expiratory pressure flow-controlled ventilation in a porcine hemorrhagic shock model.Resuscitation plus · 2025Article
- Pressure controlled ventilation with volume guarantee improves outcomes in neonatal thoracoscopic esophageal atresia surgery.Frontiers in pediatrics · 2025Article
- Individualised flow-controlled ventilation reduces applied mechanical power and improves ventilation efficiency in a porcine intra-abdominal hypertension model.Intensive care medicine experimental · 2024Article
- Understanding the mechanisms of ventilator-induced lung injury using animal models.Intensive care medicine experimental · 2023Review
- Perioperative lung function following flow controlled ventilation for robot-assisted prostatectomies in steep trendelenburg position: an observational study.Intensive care medicine experimental · 2023Article
- Article
- Commentary: Flow-controlled ventilation maintains gas exchange and lung aeration in a pediatric model of healthy and injured lungs: a randomized cross-over experimental study.Frontiers in pediatrics · 2023Article
- A new perspective during laryngo-tracheal surgery: the use of an ultra-thin endotracheal tube (Tritube®) and flow-controlled ventilation-a retrospective case series and a review of the literature.Journal of anesthesia, analgesia and critical care · 2022Article
- Flow-controlled ventilation - a new and promising method of ventilation presented with a review of the literature.Anaesthesiology intensive therapy · 2022Review
- Flow-controlled ventilation maintains gas exchange and lung aeration in a pediatric model of healthy and injured lungs: A randomized cross-over experimental study.Frontiers in pediatrics · 2022Article
- Dynamic compliance in flow-controlled ventilation.Intensive care medicine experimental · 2021Article
- A case report of individualized ventilation in a COVID-19 patient - new possibilities and caveats to consider with flow-controlled ventilation.BMC anesthesiology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFlow-controlled ventilation is a novel ventilation method which allows to individualize ventilation according to dynamic lung mechanic limits based on direct tracheal pressure measurement at a stable constant gas flow during inspiration and expiration. The aim of this porcine study was to compare individualized flow-controlled ventilation (FCV) and current guideline-conform pressure-controlled ventilation (PCV) in long-term ventilation.
methodsAnesthetized pigs were ventilated with either FCV or PCV over a period of 10 h with a fixed FiO
resultsIn FCV (n = 6), respiratory minute volume was significantly reduced (6.0 vs 12.7, MD - 6.8 (- 8.2 to - 5.4) l/min; p < 0.001) as compared to PCV (n = 6). Oxygenation was improved in the FCV group (paO
conclusionOur long-term ventilation study demonstrates the applicability of a compliance-guided individualization of FCV settings, which resulted in significantly improved gas exchange and lung tissue aeration without signs of overinflation as compared to best clinical practice PCV.
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