ArticleBMC public health2020
Protocol of the randomized control trial: the WiseApp trial for improving health outcomes in PLWH (WiseApp).
Article in BMC public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03205982 (The Wise App Trial for Improving Health Outcomes in People Living With HIV), which is not on this map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Wise App Trial for Improving Health Outcomes in People Living With HIV
Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Efficacy of CHAMPS for Improving Viral Suppression: A Randomised Clinical Trial.AIDS and behavior · 2025Trial
- Efficacy of an mHealth self-management intervention for persons living with HIV: the WiseApp randomized clinical trial.Journal of the American Medical Informatics Association : JAMIA · 2023Trial
- Establishing a usability cut-point for the health information technology usability evaluation scale (Health-ITUES).International journal of medical informatics · 2022Trial
- Social Marketing Perspective on Participant Recruitment in Informatics-Based Intervention Studies.AIDS and behavior · 2024Article
- Comparison of evaluation methods for improving the usability of a Spanish mHealth tool.International journal of medical informatics · 2024Article
- A randomized controlled trial of the dissemination of an mHealth intervention for improving health outcomes: the WiseApp for Spanish-speakers living with HIV study protocol.BMC public health · 2024Article
- Understanding Physical Activity Determinants in an HIV Self-Management Intervention: Qualitative Analysis Guided by the Theory of Planned Behavior.JMIR formative research · 2023Article
- A Smoking Cessation Mobile App for Persons Living With HIV: Preliminary Efficacy and Feasibility Study.JMIR formative research · 2022Article
- Usability assessment of a mobile app for patients with peripherally inserted central catheters.Revista latino-americana de enfermagem · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundPoor adherence to antiretroviral therapy (ART) is one of the primary barriers to viral load suppression. mHealth technology can help overcome challenges with ART adherence. This paper outlines the protocol for the WiseApp randomized control trial. The WiseApp contains real-time medication monitoring linking an electronic pill bottle and fitness tracker to the app, helping persons living with HIV (PLWH) self-manage their medication adherence and improve their overall quality of life. The primary objective of the trial is to test the effect of the WiseApp's medication adherence features on antiretroviral adherence in underserved PLWH in New York City.
methodsThis ongoing study is a two-arm randomized control trial. Participants are randomized 1:1 to the WiseApp intervention arm or the control arm at baseline and followed for 6 months. Eligibility criteria include: 18 years of age, have a diagnosis of HIV, speak and understand English or Spanish, live in the United States, own a smartphone, currently taking ART medications, and report the past 30 days adherence of 80% or less as measured using the Visual Analogue Scale (VAS), or have a viral load of over 400 copies/mL. The sample size for the trial is 200 people. All study participants receive the WiseApp, a CleverCap electronic pill bottle, and a fitness tracker. The intervention group also receives videos and health surveys centered on medication adherence and managing living with HIV as well as medication reminders. In contrast, the control group receives walk step reminders, videos, and surveys focused on overall wellness. DISCUSSION: The WiseApp Trial has the potential to improve HIV self-management applications, being one of the few randomized controlled trials of a mHealth medication adherence and HIV self-management application in the United States. The trial could also bring new opportunities for advancement in reaching economically disenfranchised and underserved populations in the United States. The real-time monitoring of the WiseApp has the potential to help providers initiate interventions to help patients resume treatment before drug resistance begins.
trial registrationThis trial was registered with ClinicalTrials.gov ( NCT03205982 ) on July 2, 2017.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.