Evidence map›Paper›PMID 33238913›Full record

ReviewBMC infectious diseases2020

Diagnosis of Streptococcus suis Meningoencephalitis with metagenomic next-generation sequencing of the cerebrospinal fluid: a case report with literature review.

Xiaobo Zhang, Zhaoping Wu, Kai Wang

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. One health (Amsterdam, Netherlands) · 2025
    Review
  2. Article
  3. Genomic characteristics of aInfectious diseases & immunity · 2025
    Article
  4. HumanTropical medicine and infectious disease · 2022
    Review
  5. ARadiology case reports · 2022
    Article
  6. Sociocultural Factors Influencing HumanFoods (Basel, Switzerland) · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Xiaobo ZhangDepartment of Neurology, The First People's Hospital Of Changde City, 818 Renmin Road, Changde, 415000, Hunan Province, China. 285058041@qq.com.
Zhaoping WuDepartment of Neurology, Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan Province, China.
Kai WangDepartment of Neurology, The First People's Hospital Of Changde City, 818 Renmin Road, Changde, 415000, Hunan Province, China.
The First People's Hospital of Changde · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStreptococcus suis meningoencephalitis is a zoonotic disease that mostly infects slaughterhouse workers. Rapid diagnosis of Streptococcus suis meningoencephalitis is critical for effective clinical management of this condition. However, the current diagnostic techniques are not effective for early diagnosis of this condition. To the best of our knowledge, the use of cerebrospinal fluid metagenomic next generation sequencing in the diagnosis of Streptococcus suis meningoencephalitis has been rarely reported. CASE PRESENTATION: Here, we report a case of Streptococcus suis meningoencephalitis in a 51-year-old female patient. The patient had a history of long-term contact with pork and had a three-centimeter-long wound on her left leg prior to disease onset. Conventional tests, including blood culture, gram staining and cerebrospinal fluid culture, did not reveal bacterial infection. However, Streptococcus suis was detected in cerebrospinal fluid using metagenomic next generation sequencing.

conclusionsMetagenomic next generation sequencing is a promising approach for early diagnosis of central nervous system infections. This case report indicates that cases of clinical meningeal encephalitis of unknown cause can be diagnosed through this method.

Indexed as

AnimalsAnti-Bacterial AgentsCeftazidimeEarly DiagnosisEncephalitisFemaleFollow-Up StudiesHigh-Throughput Nucleotide SequencingHumansMeningoencephalitisMiddle AgedStreptococcal InfectionsStreptococcus suisTreatment OutcomeZoonosesAnti-Bacterial AgentsCeftazidimeCerebrospinal fluidMeningoencephalitisMetagenomic next-generation sequencingStreptococcus suis

Identifiers

PMID33238913
PMCPMC7687824
OpenAlexW3107537046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.