Evidence map›Paper›PMID 33238833›Full record

ArticleJournal of neurotrauma2021

Impaired Glutamate Receptor Function Underlies Early Activity Loss of Ipsilesional Motor Cortex after Closed-Head Mild Traumatic Brain Injury.

Tyler Nguyen, Mohammed Haider Al-Juboori, Jakub Walerstein, Wenhui Xiong, Xiaoming Jin

Open access · greenAbstract read
In one paragraph

Article in Journal of neurotrauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  5. Review
  6. Optogenetic Interrogation of Circuits Following Neurotrauma.Frontiers in molecular neuroscience · 2021
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tyler NguyenIndiana Spinal Cord and Brain Injury Research Group, Stark Neuroscience Research Institute and Department of Anatomy, Cell Biology, and Physiology, Stark Neuroscience Research Institute and Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Mohammed Haider Al-JubooriIndiana Spinal Cord and Brain Injury Research Group, Stark Neuroscience Research Institute and Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Jakub WalersteinIndiana Spinal Cord and Brain Injury Research Group, Stark Neuroscience Research Institute and Department of Anatomy, Cell Biology, and Physiology, Stark Neuroscience Research Institute and Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Wenhui XiongIndiana Spinal Cord and Brain Injury Research Group, Stark Neuroscience Research Institute and Department of Anatomy, Cell Biology, and Physiology, Stark Neuroscience Research Institute and Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Xiaoming JinIndiana Spinal Cord and Brain Injury Research Group, Stark Neuroscience Research Institute and Department of Anatomy, Cell Biology, and Physiology, Stark Neuroscience Research Institute and Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Indiana University – Purdue University Indianapolis · USNeurosciences Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although mild traumatic brain injury (mTBI) accounts for the majority of TBI patients, the effects and cellular and molecular mechanisms of mTBI on cortical neural circuits are still not well understood. Given the transient and non-specific functional deficits after mTBI, it is important to understand whether mTBI causes functional deficits of the brain and the underlying mechanism, particularly during the early stage after injury. Here, we used

Indexed as

AnimalsBrain ConcussionBrain MappingDisease Models, AnimalMiceMice, Inbred C57BLMice, TransgenicMotor CortexMotor DisordersOptogeneticsReceptors, GlutamateTime FactorsReceptors, Glutamatecalcium imagingcontrolled cortical impactneuroplasticityoptogenetic mappingtraumatic brain injury

Identifiers

PMID33238833
PMCPMC8260891
OpenAlexW3107532590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.