ArticleJournal of neurotrauma2021
Coagulopathy as a Surrogate of Severity of Injury in Penetrating Brain Injury.
Article in Journal of neurotrauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Persistent coagulopathy after gunshot traumatic brain injury: the importance of INR and the SPIN score.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Factors Associated with the Development of Coagulopathy after Open Traumatic Brain Injury.Journal of clinical medicine · 2021Article
- Civilian Firearm-Inflicted Brain Injury: Coagulopathy, Vascular Injuries, and Triage.Current neurology and neuroscience reports · 2021Review
- Case Report: Management of Traumatic Carotid-Cavernous Fistulas in the Acute Setting of Penetrating Brain Injury.Frontiers in neurology · 2021Article
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 1 country.
Funding
Abstract
Penetrating brain injury (PBI) is the most devastating type of traumatic brain injury. Development of coagulopathy in the acute setting of PBI, though common, remains of unclear significance as does its reversal. The aim of this study is to investigate the relationship between coagulopathy and clinical presentation, radiographical features, and outcome in civilian patients with PBI. Eighty-nine adult patients with PBI at a Level I trauma center in Chicago, Illinois who survived acute resuscitation and with available coagulation profile were analyzed. Coagulopathy was defined as international normalized ratio [INR] >1.3, platelet count <100,000 /μL, or partial thromboplastin time >37 sec. Median age (interquartile range; IQR) of our cohort was 27 (21-35) years, and 74 (83%) were male. The intent was assault in 74 cases (83%). The mechanism of PBI was gunshot wound in all patients. Forty patients (45%) were coagulopathic at presentation. In a multiple regression model, coagulopathy was associated with lower Glasgow Coma Scale (GCS)-Motor score (odds ratio [OR], 0.67; confidence interval [CI], 0.48-0.94;
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Registered trials
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