Evidence map›Paper›PMID 33238786›Full record

SynthesisThe Journal of international medical research2020

Prognostic significance of autophagy-related genes

Xinbei Chen, Yang Sun, Bingrong Wang, Huihui Wang

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. The Biological Role and Clinical Significance of BECLIN-1 in Cancer.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Molecular medicine reports · 2021
    Article
  17. ATP and cancer immunosurveillance.The EMBO journal · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xinbei ChenDepartment of Gynecology, Fujian Cancer Hospital, Affiliated Cancer Hospital of 74551Fujian Medical University, Fuzhou, Fujian, China.ORCID https://orcid.org/0000-0002-4247-1148
Yang SunDepartment of Gynecology, Fujian Cancer Hospital, Affiliated Cancer Hospital of 74551Fujian Medical University, Fuzhou, Fujian, China.ORCID https://orcid.org/0000-0003-3271-1491
Bingrong WangDepartment of Gynecology, Fujian Cancer Hospital, Affiliated Cancer Hospital of 74551Fujian Medical University, Fuzhou, Fujian, China.ORCID https://orcid.org/0000-0003-2597-1033
Huihui WangDepartment of Gynecology, Fujian Cancer Hospital, Affiliated Cancer Hospital of 74551Fujian Medical University, Fuzhou, Fujian, China.
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBeclin1 plays a central role in the activation of the autophagy signaling pathway. Beclin1 and LC3-related proteins are involved in the initial steps of autophagy, which are closely related to the occurrence and development of tumors. The current meta-analysis aimed to clarify the correlation between expression of

methodsWe searched PubMed, Embase, The Cochrane Library, Web of Science, and CNKI using predefined selection criteria. Pooled hazard ratios and relative risks with 95% confidence intervals were used to evaluate the correlation between autophagy-related genes

resultsIn total, 1497 patients from 10 articles were enrolled in this meta-analysis. Expression of

conclusionsExpression of

Indexed as

Ovarian NeoplasmsAutophagyBeclin-1Carcinoma, Ovarian EpithelialFemaleHumansPrognosisBeclin-1autophagyBeclin-1LC3meta-analysisOvarian neoplasmprognosis

Identifiers

PMID33238786
PMCPMC7705295
OpenAlexW3110476259

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.