Evidence map›Paper›PMID 33238663›Full record

ArticleJournal of pathology and translational medicine2021

Causes of necrotic features in fine-needle aspirates from cervical lymph nodes.

Young Jin Seo, Hyeongchan Shin, Hye Won Lee, Hye Ra Jung

Open access · goldAbstract read
In one paragraph

Article in Journal of pathology and translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Lymph nodes in health and disease - A pathologist's perspective.Journal of oral and maxillofacial pathology : JOMFP
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Young Jin SeoDepartment of Pathology, Keimyung University Dongsan Hospital, Daegu, Korea.
Hyeongchan ShinDepartment of Pathology, Keimyung University Dongsan Hospital, Daegu, Korea.
Hye Won LeeDepartment of Pathology, Keimyung University Dongsan Hospital, Daegu, Korea.
Hye Ra JungDepartment of Pathology, Keimyung University Dongsan Hospital, Daegu, Korea.
Keimyung University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLymph node fine-needle aspiration (LN FNA) cytology indicates necrosis in various diseases. Dominant necrotic features make the diagnosis of underlying conditions very difficult.

methodsWe retrospectively reviewed 460 patients who underwent cervical LN aspiration cytology that revealed necrotic findings at Keimyung University Dongsan Hospital in Daegu, Korea, from 2003-2017. Each specimen was evaluated and analyzed in association with the clinical findings, biopsy findings, and/or other ancillary tests, including acid-fast bacilli staining and molecular testing for Mycobacterium tuberculosis.

resultsWhen necrotic features were noted upon cervical LN FNA cytology, the most common pathologic LN FNA category was necrosis alone (31.5%). The second most common category was granulomatous inflammation (31.3%), followed by Kikuchi disease (20.0%) and malignant neoplasm (8.7%). In cases where the cervical LN FNA revealed necrosis alone, the most common final diagnosis was tuberculosis. In young patients, Kikuchi disease should be considered as one cervical LN FNA category, while metastatic carcinoma should be suspected in older patients.

conclusionsEven when necrosis alone is observed in LN FNA cytology, it is important to determine the cause through further evaluation.

Indexed as

Fine-needle aspirationKikuchi diseaseLymph nodeNecrosisTuberculosis

Identifiers

PMID33238663
PMCPMC7829575
OpenAlexW3109801055

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.