Evidence map›Paper›PMID 33238649›Full record

ArticleJournal of clinical medicine2020

Changes in the Use of Fresh-Frozen Plasma Transfusions in Preterm Neonates: A Single Center Experience.

Nina A M Houben, Lisanne E Heeger, Simon J Stanworth, Helen V New, Johanna G van der Bom, Suzanne Fustolo-Gunnink, Enrico Lopriore

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Plasma transfusion in neonatal sepsis.World journal of pediatrics : WJP · 2026
    Article
  2. Article
  3. Plasma transfusions in neonatal intensive care units: a prospective observational study.Archives of disease in childhood. Fetal and neonatal edition · 2025
    Observational
  4. Article
  5. Review
  6. Review
  7. Survey of transfusion practices in preterm infants in Europe.Archives of disease in childhood. Fetal and neonatal edition · 2023
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Nina A M HoubenDivision of Neonatology, Department of Pediatrics, Leiden University Medical Center, 2333ZA Leiden, The Netherlands.ORCID 0000-0001-7605-4927
Lisanne E HeegerDivision of Neonatology, Department of Pediatrics, Leiden University Medical Center, 2333ZA Leiden, The Netherlands.
Simon J StanworthRadcliffe Department of Medicine, University of Oxford, and Oxford BRC Haematology Theme, Oxford OX3 9BQ, UK.
Helen V NewClinical Directorate, NHS Blood and Transplant, London NW9 5BG, UK.ORCID 0000-0001-6290-8004
Johanna G van der BomCenter for Clinical Transfusion Research (CCTR) LUMC/Sanquin, 1066CX Amsterdam, The Netherlands.
Suzanne Fustolo-GunninkCenter for Clinical Transfusion Research (CCTR) LUMC/Sanquin, 1066CX Amsterdam, The Netherlands.
Enrico LoprioreDivision of Neonatology, Department of Pediatrics, Leiden University Medical Center, 2333ZA Leiden, The Netherlands.
Leiden University Medical Center · NLNHS Blood and Transplant · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate changes in the use of fresh-frozen plasma (FFP) transfusions and the use of clotting tests in preterm neonates in our center over the past two decades. In this retrospective cohort analysis, we included all consecutive neonates with a gestational age at birth between 24 + 0 and 31 + 6 weeks admitted to our neonatal intensive care unit (NICU) between 2004 and 2019. We divided all included neonates into three consecutive time epochs according to date of birth: January 2004 to April 2009, May 2009 to August 2014 and September 2014 to December 2019. The main outcomes were the use of FFP transfusion, coagulation testing and the indications for FFP transfusion. The percentage of preterm neonates receiving FFP transfusion decreased from 5.7% (47/824) to 3.7% (30/901) to 2.0% (17/852) from the first epoch to the last epoch (

Indexed as

coagulation testingfresh-frozen plasma transfusionneonatal intensive care unitpreterm neonatessingle center experience

Identifiers

PMID33238649
PMCPMC7700187
OpenAlexW3109849314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.