Evidence map›Paper›PMID 33238576›Full record

ReviewJournal of clinical medicine2020

Shunt-Induced Hepatic Encephalopathy in TIPS: Current Approaches and Clinical Challenges.

Philipp Schindler, Hauke Heinzow, Jonel Trebicka, Moritz Wildgruber

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 71 citations in OpenAlex.

  1. Refractory Ascites and the Alfapump.Gastro hep advances · 2026
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  19. Hepatic hydrothorax.Journal of thoracic disease · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Philipp SchindlerInstitute of Clinical Radiology, University Hospital Muenster, D-48149 Muenster, Germany.ORCID 0000-0002-8098-9853
Hauke HeinzowDepartment of Gastroenterology and Hepatology, University Hospital Muenster, D-48149 Muenster, Germany.ORCID 0000-0001-8546-8064
Jonel TrebickaSection Translational Hepatology, Department for Internal Medicine I, Goethe University Frankfurt, D-60596 Frankfurt, Germany.ORCID 0000-0002-7028-3881
Moritz WildgruberInstitute of Clinical Radiology, University Hospital Muenster, D-48149 Muenster, Germany.ORCID 0000-0002-7228-6963
University Hospital Münster · DEGoethe University Frankfurt · DELMU Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transjugular intrahepatic portosystemic shunt (TIPS) is an established treatment tool in decompensated liver cirrhosis that has been shown to prolong transplant-free survival. Hepatic encephalopathy (HE) is a frequent complication of decompensated cirrhosis, eventually induced and/or aggravated by TIPS, that remains a clinical challenge especially in these patients. Therefore, patient selection for TIPS requires careful assessment of risk factors for HE. TIPS procedural parameters regarding stent size and invasive portosystemic pressure gradient measurements thereby have an important role. Endovascular shunt modification, in combination with a conservative medical approach, often results in a significant reduction of symptoms. This review summarizes HE molecular mechanisms and pathophysiology as well as diagnostic and therapeutic approaches targeting shunt-induced HE.

Indexed as

hepatic encephalopathyliver cirrhosistransjugular portosystemic intrahepatic shunt

Identifiers

PMID33238576
PMCPMC7700586
OpenAlexW3108532112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.