Evidence map›Paper›PMID 33238247›Full record

ArticlePhysics in medicine and biology2021

Patient's body composition can significantly affect RF power deposition in the tissue around DBS implants: ramifications for lead management strategies and MRI field-shaping techniques.

Bhumi Bhusal, Boris Keil, Joshua Rosenow, Ehsan Kazemivalipour, Laleh Golestanirad

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. A deep brain stimulation-conditioned RF coil for 3T MRI.Magnetic resonance in medicine · 2025
    Article
  6. Article
  7. Article
  8. Implants talk to each-other: RF heating changes when two DBS leads are present simultaneously during MRI.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2023
    Article
  9. Article
  10. Article
  11. The Position and Orientation of the Pulse Generator Affects MRI RF Heating of Epicardial Leads in Children.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2022
    Article
  12. Safety of MRI in patients with retained cardiac leads.Magnetic resonance in medicine · 2022
    Article
  13. Article
  14. Predicting RF Heating of Conductive Leads During Magnetic Resonance Imaging at 1.5 T: A Machine Learning ApproachAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bhumi BhusalDepartment of Radiology, Northwestern University, Chicago, IL, United States of America.ORCID 0000-0002-4404-9784
Boris KeilInstitute of Medical Physics and Radiation Protection, Mittelhessen University of Applied Sciences, D-35390 Giessen, Germany.
Joshua RosenowDepartment of Neurosurgery, Northwestern University, Chicago, IL, United States of America.
Ehsan KazemivalipourDepartment of Electrical and Electronics Engineering, Bilkent University, Ankara, Turkey.
Laleh GolestaniradDepartment of Radiology, Northwestern University, Chicago, IL, United States of America.ORCID 0000-0003-3869-6114

Funding

Patient-adjustable MRI technology for high-resolution imaging of deep brain stimulationR00EB021320 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GOLESTANI RAD, LALEH · 2018 to 2020
$733k
NIBIB NIH HHS R00 EB021320
6 · The paper itself

Abstract

Patients with active implants such as deep brain stimulation (DBS) devices have limited access to magnetic resonance imaging (MRI) due to risks associated with RF heating of implants in MRI environment. With an aging population and increased prevalence of neurodegenerative disease, the indication for MRI exams in patients with such implants increases as well. In response to this growing need, many groups have investigated strategies to mitigate RF heating of DBS implants during MRI. These efforts fall into two main categories: MRI field-shaping methods, where the electric field of the MRI RF coil is modified to reduce the interaction with implanted leads, and lead management techniques where surgical modifications in the trajectory reduces the coupling with RF fields. Studies that characterize these techniques, however, have relied either on simulations with homogenous body models, or experiments with box-shaped single-material phantoms. It is well established, however, that the shape and heterogeneity of human body affects the distribution of RF electric fields, which by proxy, alters the heating of an implant inside the body. In this contribution, we applied numerical simulations and phantom experiments to examine the degree to which variations in patient's body composition affects RF power deposition. We then assessed effectiveness of RF-heating mitigation strategies under variant patient body compositions. Our results demonstrated that patient's body composition substantially alters RF power deposition in the tissue around implanted leads. However, both techniques based on MRI field-shaping and DBS lead management performed well under variant body types.

Indexed as

Body CompositionPhantoms, ImagingProstheses and ImplantsRadio WavesDeep Brain StimulationHeatingHumansMagnetic Resonance Imaging

Identifiers

PMID33238247
PMCPMC8693336

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.