Evidence map›Paper›PMID 33237951›Full record

ArticlePloS one2020

Which feature influences on-eye power change of soft toric contact lenses: Design or corneal shape?

Tamsin Doll, Joshua Moore, Ahmad H Shihab, Bernardo T Lopes, Ashkan Eliasy, Osama Maklad, Richard Wu, Lynn White, Steve Jones, Ahmed Elsheikh and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Unraveling the impact of laser refractive surgery on corneal ectasia: anFrontiers in bioengineering and biotechnology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 5 countries.

Tamsin DollSchool of Engineering, University of Liverpool, Liverpool, United Kingdom.
Joshua MooreSchool of Engineering, University of Liverpool, Liverpool, United Kingdom.
Ahmad H ShihabSchool of Engineering, University of Liverpool, Liverpool, United Kingdom.
Bernardo T LopesSchool of Engineering, University of Liverpool, Liverpool, United Kingdom.
Ashkan EliasySchool of Engineering, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0002-4473-1900
Osama MakladSchool of Engineering, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0001-6893-2654
Richard WuDepartment of Optometry, Central Taiwan University of Science and Technology, Taichung, Taiwan.
Lynn WhiteUltravision CLPL, Leighton Buzzard, United Kingdom.
Steve JonesSchool of Engineering, University of Liverpool, Liverpool, United Kingdom.
Ahmed ElsheikhSchool of Engineering, University of Liverpool, Liverpool, United Kingdom.
Ahmed AbassSchool of Engineering, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0002-8622-4632
University of Liverpool · GBMoorfields Eye Hospital NHS Foundation Trust · GBPacific University Oregon · USUniversity of Hertfordshire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study investigates how both the peripheral zone design and corneal shape affect the behaviour of soft contact lenses on-eye.

methodsIn this study, soft contact lenses of varying nominal cylindrical powers and peripheral zone designs-a single-prism gravity-based stabilised lens (G1P), two-prism blink-based stabilised lens (B2P) and four-prism blink-based stabilised lens (B4P)-were generated as finite element models. The on-eye simulation results were analysed to identify the impact of each peripheral zone design (Each with different volume ratios) on the effective power change (EPC) when worn by a subject. Topographies of three eyes of varying average simulated anterior corneal curvature (flat, average & steep) were used in this study.

resultsThe volume of the lens's peripheral zone as a ratio of the total lens volume (Vp) recorded very weak correlations with the effective power change (EPC) among the three investigated designs when they were fitted to the flat eye (R = -0.19, -0.15 & -0.22 respectively), moderate correlations with the average eye (R = 0.42, 0.43 & 0.43 respectively) and strong correlations with the steep eye (R = 0.91, 0.9 & 0.9 respectively). No significant differences were noticed among the three investigated designs and none of the cylindrical lenses designed with axis 90° recorded EPC values outside the acceptance criteria range (ACR) of ±0.25 D. No significant differences in EPC were recorded among the three designs G1P, B2P and B4P (p>0.6) when they were designed with three axes at 90°, 45° and 0°. Moving the toric lens axis away from 90° dragged the EPC to the negative side and most of the investigated lenses with axes at 45° and 0° recorded EPCs outside the ±0.25D range.

conclusionsIn all cases, the shape of the cornea had a more dominant effect on EPC when compared to the peripheral zone design. Corneal shape influences the soft toric contact lens's on-eye power change more than the lens design.

Indexed as

Contact Lenses, HydrophilicEquipment DesignAdultCorneaCorneal TopographyFemaleFinite Element AnalysisHumansMaleYoung Adult

Identifiers

PMID33237951
PMCPMC7688134
OpenAlexW3108201420

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.